This is a Phase 1a/1b, first-in-human (FIH), open-label, multi-center dose escalation and expansion study of the safety, pharmacokinetics (PK), pharmacodynamic…

Mesothelin-Expressing TumorsEpithelial Ovarian CancerMalignant Pleural Mesothelioma, Advanced+8 more

~Estimated

~$10 – $8,750

Context Therapeutics Inc.NCT06756035

Phase 1

A Phase I Trial of Intraperitoneal Mesothelin-Targeted CAR T-Cell Therapy in Patients With Mesothelin-Positive Esophagogastric Adenocarcinoma With Peritoneal Carcinomatosis

Participants will have a sample of their white blood cells, called T cells, collected using a procedure called leukapheresis. The collected T cells will be sen…

Mesothelin PositiveMesothelin-Expressing TumorsEsophageal Adenocarcinoma+5 more

~Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT06623396