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Observational
A Master Protocol of Stereotactic Magnetic Resonance Guided Adaptive Radiation Therapy (SMART)
This is a master prospective Phase I-II trial evaluating feasibility and efficacy of stereotactic magnetic resonance (MR) guided adaptive radiation therapy (SM…
Pancreas CancerLung CancerRenal Cancer+10 more
Dana-Farber Cancer InstituteNCT04115254
Phase 1
Combination of Induction Durvalumab and Tremelimumab Alone Versus Durvalumab and Tremelimumab With Chemotherapy for Potentially Resectable Pleural Mesothelioma
Objectives: The investigators will test whether combination of chemoimmunotherapy or dual agent immunotherapy alone improves efficacy for patients with MPM. P…
Mesothelioma
Baylor College of MedicineNCT05932199
Phase 1
FIH Phase 1A /1B Study of AG01 Antibody Against Progranulin/GP88 in Advanced Solid Tumor Malignancies With Expansion Cohorts in Advanced Triple Negative Breast Ca, Hormone Resistant Breast Ca, Non Small Cell Lung Cancer and Mesothelioma
This is a first in human phase 1 study of AG01 an anti-Progranulin/Glycoprotein88 (PGRN/GP88) antibody in patients with advanced solid tumors. AG01 is a recomb…
Triple Negative Breast CancerHormone-Resistant Breast CancerNon Small Cell Lung Cancer+1 more
A&G Pharmaceutical Inc.NCT05627960
Phase 1
A Phase 1a/1b Basket Trial of BMS-986504 With Standard-of-Care Therapy For Patients With Select Metastatic MTAP-deleted Solid Tumors
The researchers are doing this study to test the safety of BMS-986504 in combination with standard disease-specific anticancer medication in people with metast…
Diffuse Pleural MesotheliomaGastroesophageal CarcinomaUrothelial Carcinoma
Memorial Sloan Kettering Cancer CenterNCT07532902