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Phase 2
Phase 2 Study of Sacituzumab Govitecan-hziy in Patients With Previously Treated Mesothelioma
Participants will receive sacituzumab govitecan until their disease gets worse (progresses), they have severe side effects and cannot continue study treatment,…
MesotheliomaMesotheliomas PleuralMesothelioma; Pleura
Memorial Sloan Kettering Cancer CenterNCT06477419
Observational
A Pilot Study of Partial Pleurectomy in Borderline and Unresectable Pleural Mesothelioma
Purpose of the study: The main purpose of this research study is to see if a surgery procedure (limited partial pleurectomy and decortication) helps symptoms i…
MesotheliomaMesothelioma; LungMesotheliomas Pleural+2 more
University of ChicagoNCT07126509
Phase 1
Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)
The study is a single-arm phase I trial to evaluate the safety, feasibility, and preliminary efficacy of the addition of pembrolizumab and image-guided resecti…
Mesotheliomas Pleural
Abramson Cancer Center at Penn MedicineNCT03760575