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119 recruiting studies matching your filters

A Phase I Dose Escalation Trial of Compartmental Radioimmunotherapy (cRIT) Using 177Lu-DTPA-omburtamab in Pediatric and Adolescent Patients With Recurrent or Refractory B7H3 Expressing Primary or Metastatic CNS Tumors

The purpose of this study is to find out whether 177Lu-DPTA-omburtamab is a safe treatment for children and adolescents with recurrent/refractory medulloblasto…

Recurrent MedulloblastomaRefractory MedulloblastomaCNS Metastases+1 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT07698899

Phase 1

A Phase I, Open Label Study Employing the Topical Immunomodulator Diphencyprone to Improve Efficacy of PD-1 or PD-L1 Immune Checkpoint Inhibition in the Treatment of Advanced Cancer With Cutaneous Metastases

This is a phase I, open label study employing diphencyprone (DPCP) to characterize gene expression changes of various immune cell and tumor markers in cutaneou…

Cutaneous Metastases

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Nicholas GulatiNCT05481658

Liver Transplantation for Unresectable Liver Limited Colorectal Metastases

This is a single-arm, single institution pilot registry of liver transplantation in patients with unresectable colorectal liver-only metastases at Weill Cornel…

Unresectable Liver-limited Colorectal Metastases

Estimated

~$10 – $750

Actual pay is set by the research site.

Weill Medical College of Cornell UniversityNCT04742621

Phase 1

A Phase 1b/2 Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of Melphalan Percutaneous Hepatic Perfusion Therapy (HEPZATO KIT™) With Nivolumab and Relatlimab (Opdualag) in Patients With Metastatic Melanoma and Liver Metastasis

This study is being done to see if combining HEPZATO KIT™ with nivolumab and relatlimab (Opdualag™) in patients with metastatic melanoma with liver metastasis …

Metastatic MelanomaLiver Metastases

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of Wisconsin, MadisonNCT07281924

Observational

An International Multicenter Randomized Controlled Trial to Compare Combined Portal and Hepatic Vein Embolization (PVE/HVE) with PVE Alone in Patients with Colorectal Liver Cancer Metastases (CRLM) and a Small Future Liver Remnant (FLR)

In the randomized controlled DRAGON 2 trial study subjects will be randomized between two arms, PVE alone (control group) and PVE/HVE (interventional group).

Colorectal Cancer Liver Metastases (CRLM)Small Future Liver Remnant (FLR)

Estimated

~$10 – $750

Actual pay is set by the research site.

Maastricht UniversityNCT05428735

Phase 2

Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance in Non-Squamous Locally Advanced Non-Small Cell Lung Cancer

The purpose of this research is to see if monitoring the brain using magnetic resonance imaging (MRI) after radiation therapy will allow investigators to find …

Brain MetastasesNonsmall Cell Lung Cancer Stage III

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Wake Forest University Health SciencesNCT05692635

7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)

Comparison of a 7t MRI to standard of care 1.5t/3t MRI scans to determine if earlier detection of brain metastases are possible on a 7t.

Small-cell Lung CancerBrain Metastases

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Missouri-ColumbiaNCT07175077

Observational

A Clinical Trial Evaluating the Efficacy of Combining Laser Interstitial Thermal Ablation With and Without Spine Stereotactic Radiosurgery for Patients With Spine Metastases

The purpose of this research is to combine two complementary modes of treatment, spinal interstitial laser ablation and stereotactic spine radiosurgery (SSRS) …

Neoplasm MetastasisSpinal Cord DiseasesSpinal Cord Compression+2 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Henry Ford Health SystemNCT05023772

Observational

A Master Protocol of Stereotactic Magnetic Resonance Guided Adaptive Radiation Therapy (SMART)

This is a master prospective Phase I-II trial evaluating feasibility and efficacy of stereotactic magnetic resonance (MR) guided adaptive radiation therapy (SM…

Pancreas CancerLung CancerRenal Cancer+10 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Dana-Farber Cancer InstituteNCT04115254

Phase 2

Risk-Stratified Adjuvant Therapy: ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver Metastases

To determine if the detection of ctDNA after surgical resection of CLM can stratify patients into high and low-risk cohorts for early disease recurrence in ord…

Liver Metastases

Estimated

~$75 – $2,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT05062317

Prospective Evaluation of Genetic and Epigenetic Alterations in Patients With Thoracic Malignancies

Background: * Chromatin is is the structural building block of a chromosome. It is found inside the nucleus of the cell and consists of a complex of DNA and p…

Thoracic CancersMalignant Pleural Mesotheliomas NOSLung Cancer NOS+3 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT00242723

Phase 2

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Intracranial Lesions: Avoidance of Eloquent White Matter and Hippocampal Regions

In this proposal, the investigators introduce advanced diffusion and volumetric imaging techniques along with innovative, automated image parcellation methods …

Brain Metastases, AdultNeurocognitive FunctionCancer+2 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Jona Hattangadi-GluthNCT04343157