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119 recruiting studies matching your filters

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Observational

MeDex: No Perioperative Dexamethasone in Brain Metastases

Perioperative treatment of newly diagnosed cancer patients with brain metastasis without dexamethasone (Dex).

Brain Metastases

Estimated

~$10 – $750

Actual pay is set by the research site.

University of LouisvilleNCT07044557

Phase 3

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead …

Bone MetastasesLymphomaMultiple Myeloma+2 more

Estimated

~$50 – $1,500

Actual pay is set by the research site.

St. Louis UniversityNCT03823534

Phase 1

Study to Identify Transcriptional Targets of Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases Receiving Preoperative Vitamin D Supplementation.

This study seeks to learn more about the vitamin D receptor and its relationship to colon cancer. The Vitamin D receptor is found in colon cancer cells. When V…

Stage, Colon CancerStage I-III Colon CancerStage IV Colon Cancer With Resectable Liver Metastases

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Dana-Farber Cancer InstituteNCT02172651

Phase 2

A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)

To learn if the study drugs, tucatinib and adotrastuzumab emtansine (T-DM1), can help to control solid tumors that have spread to the brain.

Metastatic Solid TumorBrain Metastases

Estimated

~$75 – $2,000

Actual pay is set by the research site.

M.D. Anderson Cancer CenterNCT05673928

Phase 1

A Phase 1a/1b Trial of Intrathecal Deferoxamine for Leptomeningeal Metastases

The researchers are doing this study to find out whether deferoxamine (DFO) given intrathecally (directly into the CSF) is a safe treatment for people with lep…

Leptomeningeal Metastases

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Memorial Sloan Kettering Cancer CenterNCT05184816

Phase 3

A Phase III Trial of Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Stereotactic radiosurgery (SRS) is a commonly used treatment for brain tumors. It is a one-day (or in some cases two day), out-patient procedure during which a…

Brain Metastases

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Canadian Cancer Trials GroupNCT03550391

Phase 2

The Efficacy of Pressurised Intraperitoneal Aerosol Chemotherapy (PIPAC) Combined With CURativE Intent Minimally Invasive Radical Resection in High-risk Gastric Cancer Patients. A Multicentre, Randomised, Open-label Phase-II Study

The goal of this randomized clinical trial is to investigate whether pressurized intraperitoneal chemotherapy (PIPAC), delivered immediately after minimally in…

Gastric CancerChemotherapy, AdjuvantPeritoneal Metastases+1 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Odense University HospitalNCT06295094

Phase 1

Master Protocol for A Phase 1b/2 Study of Neoadjuvant Immunotherapy in Microsatellite Stable (MSS) Colorectal Cancer (CRC) Subjects With Resectable Liver Metastases

This Phase 1b/2 trial will evaluate the safety and efficacy of neoadjuvant immunotherapy in microsatellite stable (MSS) colorectal cancer (CRC) subjects with r…

Metastatic Colorectal CancerLiver Metastases

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Dan FengNCT07277322

Phase 2

Groningen International Study on Sentinel Nodes in Vulvar Cancer-III, a Prospective Phase II Treatment Trial

Vulvar cancer patients with SN-metastasis \> 2mm will receive chemoradiation instead of an inguinofemoral lymphadenectomy.

Vulvar CancerSentinel Lymph NodeLymph Node Metastases

Estimated

~$75 – $2,000

Actual pay is set by the research site.

University Medical Center GroningenNCT05076942

Observational

A Feasibility Study of Simulation-Free, Single-Fraction Palliative Radiation Therapy for Treatment of Bone Metastases (SIM-FREE RT)

The goal of this study is to provide proof that patients can be treated with simulation-free, single-fraction palliative radiation therapy with a single in-per…

Bone Metastases

Estimated

~$10 – $750

Actual pay is set by the research site.

University of UtahNCT07202273

Observational

Phase I TITE-CREM Dose Escalation Study of Fractionated Stereotactic Radiation Therapy (FSRT) in Unresected Brain Metastases

There is a lack of prospective trial data and consensus guidelines describing the use of Fractionated Stereotactic Radiation Therapy (FSRT) in the treatment of…

Brain Metastases

Estimated

~$10 – $750

Actual pay is set by the research site.

Albert Einstein College of MedicineNCT03726359

Phase 1

Feasibility of 18F-Fluciclovine PET/CT to Identify Brain Metastasis

The goal of this diagnostic intervention clinical trial is to compare 18F-Fluciclovine uptake within brain lesions over 60 minutes compared with standard of ca…

Brain Metastases

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of ArizonaNCT06055790