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4 recruiting studies matching your filters
Phase 1
A Phase 1-2 Dose-escalation and Expansion Study of ST316 in Subjects With Selected Advanced Unresectable and Metastatic Solid Tumors
This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept efficacy of ST…
Colon CancerMetastatic Colon Cancer
Sapience TherapeuticsNCT05848739
Phase 1
A Phase 1, First-in-human (FIH), Dose-Escalation and Dose-Optimization Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic Microsatellite Stable (MSS)/Microsatellite Instability Low (MSI-L) Colorectal Cancer
This study will investigate the safety, tolerability, pharmacokinetics, and anti-tumor activity of CBI-1214 in participants with advanced or metastatic Microsa…
Colorectal CancerColorectal Cancer (CRC)Colorectal (Colon or Rectal) Cancer+4 more
Cartography BiosciencesNCT07321106
Phase 3
Early Identification and Treatment of Occult Metastatic Disease in Stage III Colon Cancer
This research study is comparing two standard of care treatment options based on blood test results for participants who have metastatic colon cancer. The nam…
Metastatic Colon CancerStage III Colon Cancer
Massachusetts General HospitalNCT03803553
Observational
Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial
This research study is a randomized controlled trial that will observe changes in microbiome activity, changes in chemotherapy toxicity, and any changes in tre…
Colorectal CancerMetastatic Colon CancerMetastatic Colorectal Cancer
Dana-Farber Cancer InstituteNCT06202183