This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in trea…

Metastatic Malignant Neoplasm in the LungMetastatic OsteosarcomaOsteosarcoma

~Estimated

~$10 – $7,500

Children's Oncology GroupNCT05235165

Phase 2

A Feasibility and Randomized Phase 2/3 Study of the VEGFR2/MET Inhibitor Cabozantinib in Combination With Cytotoxic Chemotherapy for Newly Diagnosed Osteosarcoma

This phase II/III trial tests the safety, side effects, and best dose of the drug cabozantinib in combination with standard chemotherapy, and to compare the ef…

High Grade OsteosarcomaLocalized OsteosarcomaMetastatic Osteosarcoma+1 more

~Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT05691478

Phase 2

A Phase 2 Trial of Atezolizumab and Cabozantinib in Adolescents and Young Adults With Recurrent/Metastatic Osteosarcoma (TACOS)

This phase II trial studies the effect of atezolizumab and cabozantinib in treating adolescents and young adults with osteosarcoma that has come back (recurren…

Locally Advanced OsteosarcomaMetastatic OsteosarcomaRecurrent Osteosarcoma+2 more

~Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT05019703