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Phase 2
A Randomized Clinical Trial of Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion
Mild Autonomous Cortisol Secretion (MACS) is a condition in which an adrenal gland produces excess cortisol and is associated with high blood pressure, diabete…
Mild Autonomous Cortisol Secretion (MACS)Adrenalectomy; Status
Alaa SadaNCT07573163
Detecting Mild Autonomous Cortisol Secretion in Patients With Adrenal Incidentaloma
The aim of the proposed study is to estimate the incidence of Mild Autonomous Cortisol Secretion (MACS) in patients with Adrenal Incidentaloma (AI) and evaluat…
Mild Autonomous Cortisol Secretion (MACS)
The Cleveland ClinicNCT06344143
Phase 4
Isturisa in Management of Mild Autonomous Cortisol Secretion (MACS)
To characterize the impact of Isturisa on clinical features and comorbidities associated with MACS. The investigators hypothesize that patients treated with Is…
Mild Autonomous Cortisol Secretion (MACS)
Johns Hopkins UniversityNCT07247058
Observational
IMPACT-MACS Study: Investigating the Mechanisms, Pathophysiology, and Cardiometabolic Treatment in Mild Autonomous Cortisol Secretion
The goal of this study is to learn how two treatments-adrenalectomy (surgical removal of an adrenal gland) and semaglutide (a medication used for weight manage…
Mild Autonomous Cortisol Secretion (MACS)Autonomous Cortisol Secretion (ACS)Subclinical Cushing's+1 more
University of Texas Southwestern Medical CenterNCT07361874