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8 recruiting studies matching your filters

An AI-Enabled Longitudinal Study of Energy, Symptoms, Function, and Physiology Across Mitochondrial and Energy-Limiting Conditions

Mito Map is a research tool that produces an Energy Score from information provided by a participant. This remote observational study has an initial enrollment…

Mitochondrial DiseasesMyalgic Encephalomyelitis Chronic Fatigue SyndromePost-COVID-19 Condition+8 more

Estimated

~$10 – $1,050

AI Agent Vault, Inc. d/b/a Precision MitoNCT07856121

Phase 2

An Open-label, Single-arm Extension Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of KL1333 (Napazimone) in Patients With Primary Mitochondrial Disease

The purpose of this study is to investigate if the study medicine, KL1333, is safe, well-tolerated and effective long-term in improving the symptoms of fatigue…

Mitochondrial Diseases

Estimated

~$10 – $7,500

Pharming Technologies B.V.NCT07514338

Phase 3

A Phase III, Randomised, Double-blind, Placebo-controlled, Parallel-group, Pivotal Trial to Assess the Efficacy and Safety of Sonlicromanol in Adult Subjects With a Genetically Confirmed Mitochondrial DNA tRNALeu(UUR) m.3243A>G Variant

The KHENERFIN study aims to determine whether the study medicine, sonlicromanol, is able to reduce symptoms of fatigue and the impact of fatigue on daily life,…

Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more

Estimated

~$10 – $7,500

Khondrion BVNCT06451757

Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders

The study involves up to 5 visits for a fasting blood draw, behavioral assessments, and/or questionnaires. Other samples may be collected when appropriate. Th…

Autism Spectrum DisorderMitochondrial PathologyEpilepsy+3 more

Estimated

~$10 – $1,125

Southwest Autism Research & Resource CenterNCT04322734

Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, …

Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more

Phase 1

The Utility of pGz in Primary Mitochondrial Disorders

This is a multi-aim study, studying the effects of conventional exercise (measured through Cardiopulomary Exercises Testing or an in-bed pedal exercise) and pa…

Mitochondrial MyopathiesMitochondrial Diseases

Estimated

~$10 – $6,250

Children's Hospital of PhiladelphiaNCT05569122

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disor…

Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2 more

Estimated

~$10 – $750

Columbia UniversityNCT01694940

Phase 1

The Development of Minimally Invasive Nanosensor Technology to Quantify Mitochondrial Function in Human Muscle

Past mitochondrial disease treatment studies have been unsuccessful in determining treatment efficacy, and a major factor has been the lack of validated biomar…

Mitochondrial MyopathiesMitochondrial Diseases

Estimated

~$10 – $6,250

Children's Hospital of PhiladelphiaNCT04086329