Injuries affecting the central nervous system may disrupt the cortical pathways to muscles causing loss of motor control. Nevertheless, the brain still exhibit…

Motor DisordersHealthySpinal Cord Injuries+6 more

~Estimated

~$10 – $6,250

University of Texas at AustinNCT05183152

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, i…

Movement DisordersParkinson DiseaseEssential Tremor+4 more

~Estimated

~$10 – $1,125

Abbott Medical DevicesNCT04071847

Validating a New Machine-Learned Accelerometer Algorithm Using Doubly Labeled Water

The purpose of this study is to validate previously developed physical function-clustered specific machine-learned accelerometer algorithms to estimate total d…

Movement DisordersEnergy Metabolism

~Estimated

~$10 – $750

University of Wisconsin, MilwaukeeNCT05736302

Phase 1

Safety and Efficacy of AAV9/AP4B1 For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47): A Phase 1/2 Single-Center, Open-Label Study of Stereotactic Intra-cisterna Magna Administration

Safety and Efficacy of AAV9/AP4B1 For Patients with AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47): A Phase 1/2 Single-Center, Open-Label Study of…

HSPHereditary Spastic ParaplegiaHereditary Spastic Paraparesis+10 more

~Estimated

~$10 – $8,750

BlackfinBio LtdNCT06948019

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