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5 recruiting studies matching your filters

A Phase 3, Randomized, Double-blind, Efficacy and Safety Study Comparing Orelabrutinib to Placebo in Patients With Primary Progressive Multiple Sclerosis

Orelabrutinib is a CNS-penetrable BTK inhibitor. This is a phase 3, randomized, double-blind, parallel-group, multicenter study to evaluate the efficacy and sa…

Multiple Sclerosis (MS) Primary Progressive

Estimated

~$10 – $8,750

Zenas BioPharma (USA), LLCNCT07067463

Phase 1

A Phase 1/2a, Open-Label, Dose-Escalation Study to Evaluate the Safety and Preliminary Efficacy of TRX319 in Subjects With Primary or Secondary Progressive Multiple Sclerosis

The goal of this clinical trial is to treat male and female participants with two types of Multiple Sclerosis (MS) called primary progressive or secondary prog…

Primary Progressive Multiple SclerosisSecondary Progressive Multiple Sclerosis (SPMS)Multiple Sclerosis+2 more

Estimated

~$10 – $8,750

Tr1X, Inc.NCT07477639

Phase 2

An Open-label, Single-center Study of Remibrutinib Using Ultra High-field (7T) MR Imaging in Relapsing or Progressive MS (RemiSeven)

The study is an investigator-run, study following participants for 2 years with twice-daily remibrutinib. MRI is the main endpoint. Safety, tolerability, and e…

Multiple Sclerosis (MS) - Relapsing-remittingMultiple Sclerosis (MS) Secondary ProgressiveMultiple Sclerosis (MS) Primary Progressive

Estimated

~$10 – $7,500

Moein AminNCT07222956

"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS

The goal of this observational study is to validate a novel, cost-effective method for real-world assessment using patient-acquired "selfie" videos in people w…

Multiple SclerosisMultiple Sclerosis (MS) - Relapsing-remittingMultiple Sclerosis (MS) Primary Progressive+3 more

Estimated

~$10 – $675

University of California, San FranciscoNCT07222618

Observational

Home Based Functional Balance Intervention (FBI) for Physical and Cognitive Symptoms of Multiple Sclerosis

The study involves a two-arm, Phase 1, randomized controlled clinical trial designed to establish the feasibility and effects of a Functional Balance Intervent…

Multiple SclerosisMultiple Sclerosis (MS) - Relapsing-remittingMultiple Sclerosis (MS) Primary Progressive+2 more

Estimated

~$10 – $6,250

University of Illinois at ChicagoNCT07355387