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5 recruiting studies matching your filters

An Open-Label Study to Assess the Efficacy and Safety of Multiple Doses of Salanersen (BIIB115) Delivered Intrathecally to Treatment-Naïve, Presymptomatic Infants With Genetically Diagnosed Spinal Muscular Atrophy

In this study, researchers will learn more about the effects and safety of BIIB115, also known as salanersen. Specifically, researchers will learn more about …

Muscular Atrophy, Spinal

Estimated

~$50 – $2,250

Actual pay is set by the research site.

BiogenNCT07221669

Phase 4

A Phase IV Open-Label Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Patients With Spinal Muscular Atrophy After Gene Therapy

This is an open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam administered as an early intervention in pe…

Muscular Atrophy, Spinal

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Hoffmann-La RocheNCT05861986

Spinraza (Nusinersen) SMA Pregnancy Exposure Study Within Existing SMA Registries

In this study, researchers will know more about the effects of nusinersen, also known as Spinraza®, in pregnant participants with spinal muscular atrophy, also…

Muscular Atrophy, Spinal

Estimated

~$10 – $1,125

Actual pay is set by the research site.

BiogenNCT05789758

Phase 3

A Phase 3, Randomized, Double-Blinded Study to Evaluate the Safety and Efficacy of Salanersen (BIIB115) After Onasemnogene Abeparvovec Treatment in Infants With Genetically Diagnosed Spinal Muscular Atrophy

In this study, researchers will learn more about the safety and effects of BIIB115, also known as salanersen. Specifically, researchers will learn more about h…

Muscular Atrophy, Spinal

Estimated

~$50 – $2,250

Actual pay is set by the research site.

BiogenNCT07444450

Phase 1

An Open Label Study to Assess the Pharmacokinetic Profile of Nusinersen (BIIB058) Administered Via the ThecaFlex DRx™ System (PIERRE-PK)

In this PIERRE-PK study, researchers will learn how the body processes nusinersen when it is given through the ThecaFlex DRx™ System, compared to when nusiners…

Muscular Atrophy, Spinal

Estimated

~$150 – $4,500

Actual pay is set by the research site.

BiogenNCT06555419