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100-Year Human Aging Study: Prospective Longitudinal Validation of Multi-System Health Measurements Against Mortality and Aging Outcomes
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed and mobile clinical sites to undergo compre…
AgingAging WellAll-Cause Mortality+12 more
Longevity Metrics, Inc.NCT07563777
Observational
Anabolic Versus Catabolic Skeletal Effects of Endurance or Resistance Exercise in Older Veterans
Adults are often encouraged to exercise to maintain or improve bone health. However, there is evidence that exercise does not always lead to increases in bone …
AgingMusculoskeletal DiseasesOsteoporosis
VA Office of Research and DevelopmentNCT05266976
Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry
Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clini…
Bone Diseases, InfectiousMusculoskeletal DiseasesJoint Diseases+3 more
Xiaojuan LiNCT04536103
Observational
The Effects of AFO Heel Height and Stiffness on Gait
The proposed study evaluates the effect of ankle foot orthosis (AFO) heel height and stiffness on the forces and motion of the lower limb during over-ground wa…
Musculoskeletal InjuryMusculoskeletal DiseasesPeripheral Nervous System Diseases
University of IowaNCT04800484