This phase I trial tests the safety, side effects, and best dose of SM08502 (cirtuvivint) alone and in combination with ASTX727 in treating patients with acute…

Acute Myeloid LeukemiaMyelodysplastic SyndromeMyelodysplastic Syndrome/Acute Myeloid Leukemia+6 more

~Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06484062

Phase 1

A Phase Ib Investigation of the LSD1 Inhibitor Iadademstat (ORY-1001) in Combination With Azacitidine and Venetoclax in Newly Diagnosed AML

This phase I trial tests the safety, side effects, and best dose of iadademstat when given together with azacitidine and venetoclax in treating patients with n…

Acute Myeloid LeukemiaMyelodysplastic Syndrome/Acute Myeloid Leukemia

~Estimated

~$10 – $7,500

OHSU Knight Cancer InstituteNCT06357182