Browse Studies — Arctuva

Phase 1

A Phase I Study of Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Other Hematologic Malignancies

Background: Blood cancers (such as leukemias) can be hard to treat, especially if they have mutations in the TP53 or RAS genes. These mutations can cause the …

Malignancy, HematologicNeoplasms, HematologicNeoplasms, Hematopoietic+8 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06904066

Observational

A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers

This is a multicenter randomized controlled trial that assesses the efficacy of a decisional intervention \[University of Rochester-Geriatric Oncology assessme…

OncologyMyeloid Leukemia, AcuteCancer

Estimated

~$10 – $6,250

University of RochesterNCT06697600

Phase 1

A Pilot/Phase 1 Study of Immunosuppression-free Regulatory T-cell Graft-engineered Haploidentical Hematopoietic Cell Transplantation in Relapsed/Refractory and Ultra-High-risk AML/MDS

This research study is evaluating the safety and efficacy of the IS-free Treg-cell graft-engineered haplo transplant method in people with relapsed/refractory …

Stem Cell Transplant ComplicationsGraft Vs Host DiseaseMyeloid Leukemia, Acute+2 more

Estimated

~$10 – $7,500

Dana-Farber Cancer InstituteNCT04678401