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112 recruiting studies matching your filters

Left Ventricular Structural Predictors of Sudden Cardiac Death [Substudy of: Functional Energetics and Imaging for Phenotypic Characterization of Patients at Risk for Sudden Cardiac Death, See Also NCT000181233]

Sudden cardiac death (SCD) poses a significant health care challenge with high annual incidence and low survival rates. Implantable cardioverter defibrillators…

Ischemic CardiomyopathyNonischemic Cardiomyopathy

Estimated

~$10 – $750

Johns Hopkins UniversityNCT01076660

The International Registry for Leigh Syndrome

The purpose of this study is to develop a database containing clinical and laboratory information for patients with Leigh syndrome. The goal is to provide a gr…

Leigh SyndromeLeigh DiseaseLeigh's Necrotizing Encephalopathy+2 more

Estimated

~$10 – $750

The University of Texas Health Science Center, HoustonNCT03137355

Myotonic Dystrophy Family Registry

The Myotonic Dystrophy Family Registry (MDFR) is an online, patient-entered database that collects information on myotonic dystrophy (DM) to aid researchers in…

Myotonic DystrophyCongenital Myotonic DystrophyMyotonic Dystrophy 1+13 more

Estimated

~$10 – $750

Myotonic Dystrophy FoundationNCT02398786

Nemaline Myopathy Clinical Research Network (NM-CTRN)

The goal of this study is to establish a research network to help define the natural disease history and clinical outcome measures for Nemaline Myopathy (NM).

Nemaline Myopathy

Estimated

~$10 – $750

Stanford UniversityNCT06774703

Coordination of Rare Diseases at Sanford

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, …

Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more

Observational

Novel Magnetic Resonance Imaging Techniques for Quantitative Cardiac Parametric Mapping

The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac M…

Cardiomyopathy, Myocarditis, Ischemic Heart Disease

Estimated

~$10 – $6,250

Medical University of South CarolinaNCT02855554

Phase 1

First-in-Human, Open-Label, Safety, Tolerability, Dose-Finding, Pharmacodynamic and Cardiac Transgene Expression Study of TN-201, a Recombinant Adeno-associated Virus Serotype 9 (AAV9) Containing Myosin Binding Protein C Transgene, in Adults With MYBPC3 Mutation-associated Hypertrophic Cardiomyopathy (HCM)

This is a first-in-human, non-randomized, open-label study designed to evaluate the safety, tolerability, and pharmacodynamics (PD) of TN-201 in adult patients…

Hypertrophic Cardiomyopathy

Estimated

~$10 – $8,750

Tenaya TherapeuticsNCT05836259

Seroprevalence Study of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

This is a multicenter, non-interventional study to observe the natural progression of the disease and to study the prevalence of pre-existing antibodies to AAV…

Arrhythmogenic Right Ventricular Cardiomyopathy

Estimated

~$10 – $1,050

Tenaya TherapeuticsNCT06311708

Coronary Flow Reserve in oHCM Patients Before and After 12 Months of Standard-of-care Mavacamten Treatment as Assessed by PET/CT

The goal of this observational study is to measure the effect of mavacamten treatment on blood flow in the heart muscle (myocardium) in patients with obstructi…

Obstructive Hypertrophic Cardiomyopathy

Estimated

~$10 – $1,125

Michael AyersNCT06023186

A Prospective Study to Assess Multi-Domain Patient-Reported Cardiac Quality of Life in Adults With Hypertrophic Cardiomyopathy, Thoracic Aortopathy, and Radiation-Induced Heart Disease: UPLIFT

A prospective, longitudinal, non-comparator, non-randomized observational cohort study to assess the quality of life in adult patients affected by hypertrophic…

Hypertrophic Obstructive CardiomyopathyThoracic Aortic DilatationHeart Disease Caused by Ionising Radiation+1 more

Estimated

~$10 – $750

The Cleveland ClinicNCT04080492

Single Center Pilot Study of Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables

Congenital heart disease (CHD) includes a wide variety of types of disease, including congenital abnormalities of the heart valves. This can range from bicuspi…

Congenital Heart DiseaseCongenital Vascular DisorderCongenital Cardiomyopathy+1 more

Estimated

~$10 – $750

The Cleveland ClinicNCT06818760

Phase 1

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy

The goal of this clinical trial is to learn if sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, works to treat symptomatic, nonobstructive hypertrophic cardiom…

Hypertrophic Cardiomyopathy Without Obstruction

Estimated

~$10 – $6,250

University of PennsylvaniaNCT06433050