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36 recruiting studies matching your filters

OBServation of Environment and ReproductiVe Endocrine Effects Study (OBSERVE Study)

Background: Endocrine disorders occur when the glands that make hormones do not work properly. Hormones levels that are too high or too low can cause problems…

HypogonadismHypergonadismPrecocious Puberty+2 more

Estimated

~$10 – $675

National Institute of Environmental Health Sciences (NIEHS)NCT06280807

Phase 1

A Phase 1/2 Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Selected Advanced or Metastatic Solid Tumors

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary antitumor activity of BGB-B203…

Metastatic Hepatocellular CarcinomaLocal Advanced Hepatocellular CarcinomaAlpha-fetoprotein (AFP)-Producing Gastric Cancer+2 more

Estimated

~$10 – $7,500

BeOne MedicinesNCT06427941

Observational

Anti-inflammatory Activities of Vitamin C Supplementation on the Gut Barrier Function in Adults With Obesity

This study is testing whether taking vitamin C every day can help improve gut health and reduce inflammation in adults with obesity. Poor gut health-sometimes …

Adequate Vitamin C StatusInadequate Vitamin C Status

Estimated

~$10 – $6,250

Ohio State UniversityNCT07151105

Phase 3

A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is r…

Childhood Extracranial Germ Cell TumorExtragonadal Embryonal CarcinomaGerm Cell Tumor+27 more

Phase 4

Musculoskeletal Resiliency and Adaptation to Sex Steroid Suppression and Replacement During Multi-Stressor Training

Non-combat-related muscle, tendon and bone injuries are the most common injuries suffered by military personnel, particularly in new recruits. These injuries i…

Musculoskeletal InjuryHypogonadismHormonal Contraception

Estimated

~$10 – $7,500

Bradley NindlNCT06455969

Phase 2

A Multisite, Double-blind, Randomized Controlled Trial Comparing Body Composition, Muscle, and Bone Changes to TestosteRone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial

Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture …

Spinal Cord InjurySpinal Cord InjuriesInjuries, Spinal Cord+11 more

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT07742553

The Molecular Basis of Inherited Reproductive Disorders

Background: \- During puberty, children begin to develop into adults. Problems with the hormones released during puberty can affect the reproductive system. S…

Genetic DisorderInfertilityHypogonadism+1 more

Estimated

~$10 – $675

National Institute of Environmental Health Sciences (NIEHS)NCT01500447

Phase 2

Androgen Replacement to Improve Patient-Important Outcomes in Men With Opioid-Induced Hypogonadism

The aim of this trial is to evaluate whether testosterone replacement results in greater improvement in pain perception, pain tolerance, sexual function, fatig…

Opioid UsePainHypogonadism, Male

Estimated

~$10 – $6,250

Brigham and Women's HospitalNCT04798469

Detection of Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors Exposed to Cisplatin-based Chemotherapy and Bone Marrow Transplant

Late subclinical cardiovascular disease in testicular cancer survivors exposed to cisplatin-based chemotherapy and bone marrow transplant

Testicular CancerSurvivorshipASCVD+5 more

Estimated

~$10 – $750

Indiana UniversityNCT05611307

Phase 4

Safety of Intramuscular Testosterone Replacement Therapy in Hypogonadal Patients With Prostate Cancer Under Active Surveillance

The purpose of this study is evaluate the safety of testosterone replacement therapy in men with newly diagnosed low-risk prostate cancer and hypogonadism on a…

Prostate CancerHypogonadism, Male

Estimated

~$10 – $6,250

University of MiamiNCT07278362

Observational

Expiratory Muscle Strength Training as a Non-surgical Option for Velopharyngeal Dysfunction: A Randomized-controlled Trial

When the soft palate does not move enough because of a cleft palate or for unknown reasons, this can lead to a speech difference called velopharyngeal insuffic…

Velopharyngeal InsufficiencyVelopharyngeal Incompetence Due to Cleft PalateInadequate Velopharyngeal Closure+2 more

Estimated

~$10 – $7,500

Noel JabbourNCT05492266

Observational

Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients: Enhancing Technological Innovation and Strengthening the Role of Small Businesses in Meeting Needs of Adolescent Organ Transplant

We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nona…

Heart Transplant RejectionImmune SuppressionPediatric Heart Transplant+4 more

Estimated

~$10 – $6,250

University of FloridaNCT05732779