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125 recruiting studies matching your filters

A Prospective Multicenter Trial Evaluating the Safety and Effectiveness of Endo-SPONGE for the Treatment of Anastomotic or Hartmann's Stump Leakages in the Lower Pelvic Area

This study is intended to evaluate the safety and effectiveness of Sponge-based Endoscopic Vacuum Therapy (EVT) using Endo-SPONGE for the treatment of Anastomo…

Anastomotic LeaksHartmanns Stump Leakage

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Boston Scientific CorporationNCT07035431

Observational

A Prospective Multicenter Trial Evaluating the Safety and Effectiveness of Eso-SPONGE for the Treatment of Anastomotic Leaks in the Upper Gastrointestinal Tract

To evaluate the safety and effectiveness of sponge-based Endoscopic Vacuum Therapy (EVT) using Eso-SPONGE for the treatment of anastomotic leaks in the upper g…

Anastomotic Leaks

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Boston Scientific CorporationNCT07711093

Phase 3

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis due to N…

NASH - Nonalcoholic SteatohepatitisMASH - Metabolic Dysfunction-Associated Steatohepatitis

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Akero Therapeutics, IncNCT06528314

Phase 2

A Phase IIb Randomized, Double-blind, Placebo-controlled, Parallel, Multidose Study to Evaluate the Efficacy, Safety, and PK of AZD0292 in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

AZD0292 is a bispecific IgG1k mAb being evaluated for the prevention of exacerbations in bronchiectasis patients chronically colonized with PsA.

Bronchiectasis With Pseudomonas Aeruginosa Colonization

Estimated

~$75 – $3,000

Actual pay is set by the research site.

AstraZenecaNCT07088926

Observational

A Multicenter, Randomized, Controlled Study to Evaluate the Safety and Effectiveness of a Bioresorbable Nasal Dressing Containing Mometasone Furoate Compared to a Steroid-eluting Sinus Stent

The primary objective of the study is to evaluate the safety and effectiveness of OCEAN as an adjunct aid in wound healing after nasal/sinus surgery and to dem…

Chronic Rhinosinusitis (CRS)Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Polyganics BVNCT07286201

Observational

Cartilage Remodeling Using Low-Temperature Radiofrequency for Facial Reconstruction

The goal of this study is to evaluate the efficacy of using the Vivaer low-temperature radio-frequency (LTRF) device to reshape ex-vivo human nasal or auricula…

Nasal Valve CollapseNose Enhancement

Estimated

~$10 – $750

Actual pay is set by the research site.

Indiana UniversityNCT07032675

Prospective Study of the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Background: Pyrimidine and purine metabolism disorders (DPPMs) affect how the body metabolizes chemicals called pyrimidines and purines. DPPMs can cause dysfu…

AMPD3, OMIM*102772, AMP Deaminase DeficiencyAK1, OMIM *103000, Adenylate Kinase DeficiencyAMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency+25 more

Natural History of Multiple Acyl-CoA Dehydrogenase Deficiency (MADD)

The objective of this study is to conduct a longitudinal, observational investigation to determine the natural history of Multiple Acyl-CoA Dehydrogenase Defic…

Multiple Acyl-CoA Dehydrogenase Deficiency

Estimated

~$10 – $750

Actual pay is set by the research site.

Icahn School of Medicine at Mount SinaiNCT07734090

Phase 4

Refining Treatment Options for Trichomonas Vaginalis Infection in Women and Men: A Comparative Analysis of Oral Multi-Dose Metronidazole and Single-Dose Secnidazole

This is a multi-centered, randomized, open-label, parallel, phase IV clinical trial comparing the effectiveness and cost-effectiveness of oral multi-dose metro…

Trichomonas VaginitisBacterial Vaginitis

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Tulane UniversityNCT06261840

Phase 2

A Single-arm Extension Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Lunsekimig in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Clinical Study

This is a single-arm extension study to investigate the long-term safety, tolerability, and efficacy of lunsekimig in adult participants with inadequately cont…

Chronic Rhinosinusitis With Nasal Polyps

Estimated

~$75 – $3,000

Actual pay is set by the research site.

SanofiNCT06914908

Phase 3

A Randomized, Double-blind, Parallel Group Phase 3 Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) (PERSIST CRSwNP-2)

The aim of this study is to assess the efficacy and safety of GSK5784283 administered as add-on maintenance therapy to participants with CRSwNP.

Nasal Polyps

Estimated

~$50 – $2,250

Actual pay is set by the research site.

GlaxoSmithKlineNCT07782957

Phase 3

Comparison of Outcomes in Rhinoplasty With the Use of Intraoperative Versus Postoperative Antibiotics

This study compares the efficacy of a single intra-operative (intravenous) dose of "cephalexin" (first generation cephalosporin) or "clindamycin" (lincosamides…

Nasal ObstructionNasal Surgical Procedures

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Stanford UniversityNCT04194216