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181 recruiting studies matching your filters

Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma

This is a pilot study; patients will receive 131-I apamistamab prior to CAR T-cell infusion in order to determine the maximum tolerated dose of 131-I apamistam…

B-ALLDLBCLB ALL+8 more

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT04512716

Observational

Bundled Cancer Screening and Genetic Services Navigation

The goal of this study is to test bundled familial cancer risk assessment + multicancer (colorectal + breast) vs. single (breast) cancer navigation, using a wa…

Breast Cancer ScreeningColon Cancer ScreeningGenetics Predisposition

Estimated

~$10 – $6,250

Georgetown UniversityNCT07228000

Phase 1

A Randomized, Double-Blind, Vehicle-Controlled, First-in-Human Safety, Tolerability and Proof-of-Concept Study of Topical ATR12-351 in Adults With Netherton Syndrome

The objectives of this clinical trial are to evaluate the safety and tolerability of topically applied ATR12-351, to understand what the body does to ATR12-351…

Netherton Syndrome

Estimated

~$10 – $8,750

Azitra Inc.NCT06137157

Vaginal Metabolome Healthy Volunteers Study

The purpose of this study is to examine the role of the bacterial environments and metabolites in the early detection and prediction of ovarian cancer developm…

Ovarian CancerGenetic Predisposition to Disease

Estimated

~$10 – $750

Abramson Cancer Center at Penn MedicineNCT06962059

Phase 1

A Phase 1, Multi-Center, Open-Label Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Sulopenem Etzadroxil + Probenecid in Adolescent Patients With Bacterial Infection

The goal of this clinical trial is to evaluate the use of sulopenem etzadroxil plus probenecid in adolescent patients being treated for bacterial infection. Th…

Pharmacokinetics After Oral Intake

Estimated

~$10 – $8,750

Iterum Therapeutics, International LimitedNCT07092813

Characterization of the Natural History of Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation

In this study, we will conduct retrospective chart and imaging reviews and prospective longitudinal virtual assessments of individuals with LBSL.

LeukoencephalopathiesLBSLLeukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation+3 more

Estimated

~$10 – $1,050

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.NCT03624374

Neurogenetics Program Patient Registry: Clinical and Genetic Diagnosis, Natural History Study, Translational Research and Biorepository

The objective of this project is to develop a Neurogenetics patient database and bio repository - which includes clinical information regarding history, physic…

Neurogenetic Disorders

Estimated

~$10 – $750

University of PittsburghNCT02995538

Phase 2

Phase II, Open-Label, Prospective Study of T Cell Receptor Alpha/Beta Depletion (A/B TCD) Peripheral Blood Stem Cell (PBSC) Transplantation for Children and Adults With Hematological Malignancies

This is a phase II, open-label, prospective study of T cell receptor alpha/beta depletion (TCR α/β TCD) peripheral blood stem cell (PBSC) transplantation for c…

Hematologic MalignancyAcute LeukemiaRemission+21 more

Estimated

~$10 – $6,250

Masonic Cancer Center, University of Minnesota

Phase 3

Phase 1b/3 Global, Randomized, Controlled, Open-label Trial Comparing Treatment With RYZ101 to Standard of Care Therapy in Subjects With Inoperable, Advanced, SSTR+, Well-differentiated GEP-NETs That Have Progressed Following Prior 177Lu-SSA Therapy

This study aims to determine the safety, pharmacokinetics (PK) and recommended Phase 3 dose (RP3D) of RYZ101 in Part 1, and the safety, efficacy, and PK of RYZ…

GEP-NETGastroenteropancreatic Neuroendocrine TumorGastroenteropancreatic Neuroendocrine Tumor Disease+4 more

Estimated

~$10 – $8,750

RayzeBio, Inc.NCT05477576

Observational

Genetic and Environmental Contributions to Obesity Pathogenesis

The goal of this research is to investigate genetic and environmental factors that contribute to obesity through brain inflammation. The main questions are 1) …

GeneticsObesity

Estimated

~$10 – $6,250

University of WashingtonNCT07430852

Observational

Effect of Increasing Fluence on Efficacy of Low Level Laser Therapy for Androgenetic Alopecia, a Randomized Control Trial

Androgenetic alopecia (AGA) is a prevalent disease, occurring in 80% of Caucasian men and 50% of Caucasian women by age 701. Treatments for AGA are limited, an…

Androgenetic Alopecia

Estimated

~$10 – $6,250

University of ArizonaNCT05365360

Phase 1

COMMENCER: COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER

This is research study is assessing the effects of 6-g daily use of freeze-dried instant coffee on liver fat and fibrosis and the gut microbiome and metabolome…

Colorectal CancerCoffeeGastrointestinal Microbiome+4 more

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT05692024