Find your next paid study

Children's Hospital of PhiladelphiaNCT07554560

Phase 1

A Multicenter, Open-label, Phase 1b Study to Assess the Pharmacokinetics, Safety, and Tolerability of Sulbactam-Durlobactam in Hospitalized Pediatric Patients From Birth to <18 Years Who Are Receiving Systemic Antibiotic Therapy for Suspected or Confirmed Acinetobacter Baumannii-calcoaceticus Complex Infection

The goal of this clinical trial is to investigate the use of Sulbactam-Durlobactam (SUL-DUR) in pediatric patients and is being conducted to collect pharmacoki…

Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC)

Innoviva Specialty TherapeuticsNCT06801223

~$10 – $8,750

Phase 2

Microbiome and Association With Implant Infections: Investigating the Impact of Antibiotics on the Gut and Breast Microbiomes Post-mastectomy With Implant-based Breast Reconstruction

The most common tissue expander-related infections are from Staphylococcus and Pseudomonas species. In addition, from breast tissue microbiome studies, Staphyl…

Breast CancerBreast Cancer FemaleGenetic Predisposition to Disease

University of California, San FranciscoNCT05020574

~$10 – $5,625

Juxtarenal Aortic AneurysmSuprarenal Aortic AneurysmThoracoabdominal Aortic Aneurysm+3 more

Evaluation of All-Cause Mortality and Pulmonary Morbidity in Treating Juxtarenal, Suprarenal, Thoracoabdominal, and Aortic Arch Pathologies Using Cook Custom Aortic Endografts, the Zenith t-Branch Endovascular Graft, and the Surgeon-Modified Endograft

This is a single-center study to evaluate the safety and effectiveness of three investigational devices, the Cook Custom Aortic Endograft, the Zenith t-Branch …

University of Alabama at BirminghamNCT02043691

Whole Exome Sequencing and Whole Genome Sequencing for Nonimmune Fetal/Neonatal Hydrops

Brief Summary: Nonimmune hydrops fetalis (NIHF) is a potentially fatal condition characterized by abnormal fluid accumulation in two or more fetal compartments…

Nonimmune Fetal HydropsNonimmune Hydrops in NeonateGenetic Disorders

Thomas Jefferson UniversityNCT03911531

~$10 – $750

Long QT SyndromeFamilial HypercholesterolemiaEthics+1 more

Comparing Direct and Indirect Methods for Cascade Screening in Familial Hypercholesterolemia (FH) and Long QT Syndrome (LQTS)

An important aspect of successful genomic medicine implementation is developing effective approaches for screening at-risk family members after probands are id…

University of Maryland, BaltimoreNCT05348564

Hypertrophic Cardiomyopathy (HCM)CardiomyopathyGenetic Disease+1 more

Towards Bridging Generalists to Subspecialists With Large Language Models

This study evaluates the impact of large language models (LLMs) versus traditional decision support tools on clinical decision-making in cardiology. General ca…

Stanford UniversityNCT06935253

Phase 2

Functional Neuroimaging of the Enhanced Antidepressant Efficacy of Ketamine in a Biologically-Enriched Subgroup

A single subanesthetic dose infusion of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine has rapid and robust antidepressant effects in patients wi…

Magnetic Resonance ImagingMajor DepressionAlcoholism

CardiomyopathiesHeart DiseasesCardiovascular Diseases+1 more

~$10 – $7,500

Mark NiciuNCT02122562

The Natural History of Arrhythmogenic Cardiomyopathy With Pathogenic Plakophilin-2 Variants (PKP2-ACM): An Observational Cohort Study

The goal of this study is to describe the natural history and clinical events for patients who have Arrhythmogenic Cardiomyopathy with Pathogenic Plakophilin-2…

Rocket Pharmaceuticals Inc.NCT06644742

~$10 – $1,050

Phase 1

A Phase I, Open Label, Study of 3,4-Methylenedioxymethamphetamine (MDMA) Tolerability and Pharmacokinetics in Subjects With Moderate Hepatic Impairment Compared to Matched Control Subjects With Normal Hepatic Function

The goal of this clinical trial to learn how MDMA is processed in people with abnormal liver function. The main questions it aims to answer are: Do people wi…

PharmacokineticsHepatic Impairment

Resilient PharmaceuticalsNCT03606538

~$10 – $8,750

Aortic DissectionIntramural HematomaPenetrating Ulcer+1 more

Proposed Single Center Investigational Device Exemption: Feasibility of Endovascular Repair Of Ascending Aortic Pathologies

The purpose of this study is to investigate the outcome of patients with pathologies of the ascending thoracic aorta (diseases in the great blood vessel or art…

Rodney A. White, MDNCT02201589

~$10 – $7,500

Myeloid MalignancyGenetic Predisposition to DiseaseMyeloid Hematological Malignancies

MyeloGen: Germline Testing for Predisposition to Myeloid Malignancies

The goal of this research study is to evaluate the feasibility of germline genetic testing using the investigational MyeloGen Gene Panel in adult participants …