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Phase 1
A Phase 1, First-in-human Study Evaluating the Safety, Tolerability, and Pharmacokinetics of VX-433 and Its Effects on the Pharmacokinetics of Midazolam and Bupropion
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of VX-433 following single and multiple ascending doses, as well a…
Narcolepsy Type 1 (NT1)
Estimated
~$10 – $8,750
Vertex Pharmaceuticals IncorporatedNCT07584434
Phase 3
A Double-blind, Placebo-Controlled, Randomized Withdrawal Trial to Evaluate the Efficacy and Safety of TAK-861 for the Treatment of Narcolepsy With Cataplexy (Narcolepsy Type 1)
The main aim of this study is to assess how effective TAK-861 is for treating narcolepsy type 1 and if this effect is maintained over time. Participants will t…
Narcolepsy Type 1 (NT1)Narcolepsy With Cataplexy
Estimated
~$10 – $7,500
TakedaNCT07363720