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Phase 2
The Effects of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals (NAUTICAL)
Black individuals are more likely to have decreased insulin sensitivity which results in a high risk for the development of cardiometabolic disease. The reason…
Diabetes MellitusCardiovascular DiseasesInsulin Sensitivity/Resistance+4 more
University of Alabama at BirminghamNCT04055428
Observational
Atrial Natriuretic Peptide and Regulation of Cardiometabolic Health: A Genotype-Guided Human Physiological Study
Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are as…
Cardiovascular DiseasesNatriuretic PeptidesCardiometabolic Diseases+4 more
University of Alabama at BirminghamNCT05216042
UAB Cardiovascular Research Biobank
The UAB Cardiovascular Research Biobank (CARBON) will be a resource that contains biological materials, such as DNA samples, in addition to health and personal…
Natriuretic PeptidesCardiovascular DiseasesHypertension+2 more
University of Alabama at BirminghamNCT05067231
Phase 2
Natriuretic Peptide-Renin-Angiotensin-Aldosterone System Rhythm Axis and Nocturnal Blood Pressure
Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased ris…
ObesityCardiovascular DiseasesHypertension+3 more
University of Alabama at BirminghamNCT04971720