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27 recruiting studies matching your filters

Evaluation of a Point-of-Care, AI-Powered Spectroscopy Device for Triage of Suspicious Vulvar Lesions: A Pilot Study

This purpose of this study is to assess the feasibility of using the DermaSensor™ device on vulvar skin.

Vulvar Intraepithelial Neoplasia, HPV-IndependentVulvar Squamous Cell CarcinomaVulvar Squamous Intraepithelial Lesion, HPV-Associated

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT07886203

Phase 1

A Phase I Open Label, Dose Escalation Clinical Trial Assessing the Safety, Tolerability, and Feasibility of pNGVL4aCRTE6E7L2 HPV DNA Vaccine Administration Via Intramuscular TriGridTM Electroporation Delivery System to Patients With HPV16-Positive High-Grade Cervical Intraepithelial Neoplasia

The primary goal of this phase I open label study is to determine the safety and tolerability of pNGVL4aCRTE6E7L2 DNA vaccine, as administered by intramuscular…

Human Papillomavirus Type 16Cervical Intraepithelial Neoplasia Grade IICervical Intraepithelial Neoplasia, Grade III

Estimated

~$500 – $7,500

Actual pay is set by the research site.

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT04131413

Incidental Detection of Maternal Neoplasia Through Non-invasive Cell-Free DNA Analysis (IDENTIFY), a Natural History Study

Background: Pregnant women can get a DNA analysis of their blood. The test tells a woman and her doctor about the DNA of her unborn baby. But some women get t…

Maternal Neoplasia

Estimated

~$10 – $675

Actual pay is set by the research site.

National Human Genome Research Institute (NHGRI)NCT04049604

Phase 2

A Phase II Double-blind, Placebo-controlled, Randomized Trial of Topical Artesunate Ointment for the Treatment of Patients With Vulvar High-grade Squamous Intraepithelial Lesions (Vulvar HSIL)

This is a phase II double-blind, placebo-controlled study of artesunate ointment for the treatment of HPV-associated vulvar HSIL (usual type vulvar intraepithe…

Vulvar DiseasesHPV InfectionVulvar HSIL+10 more

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Frantz Viral Therapeutics, LLCNCT06075264

Registry and Biosample Repository

The goal of this study is to establish a registry and biosample repository (defined as blood, urine, and tumor specimens) in patients with a cancer and/or beni…

Neoplasia

Estimated

~$10 – $750

Actual pay is set by the research site.

Abramson Cancer Center at Penn MedicineNCT01577251

Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies

Background: Gene therapy is closely followed by the U.S. Food and Drug Administration (FDA). The FDA requires researchers to conduct long-term follow-up of pe…

Cervical Intraepithelial NeoplasiaCervical NeoplasmsOropharyngeal Neoplasms+2 more

Estimated

~$10 – $675

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT04266093

The LINFU® (A Noninvasive Method for Increasing Exfoliation of Pancreatic Ductal Cells Into Pancreatic Fluid) U.S. Registry for the Detection of Low and High- Grade Atypia and Early, Asymptomatic Pancreatic Ductal Adenocarcinoma (PDAC)

Adenocyte has developed LINFU®, (Low Intensity Non-Focused Ultrasound excitation of the pancreas) as a method of identifying early, asymptomatic pancreatic can…

Pancreatic AdenocarcinomaPancreatic Intraepithelial Neoplasia

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Adenocyte, LLCNCT06157671

Phase 2

Semaglutide, Weight Loss, And Intrauterine Therapy For Fertility-Sparing And Conservative Treatment For Endometrial Atypical Hyperplasia And Early-Stage, Grade 1 Endometrioid Endometrial Cancer

The goal of this clinical trial is to learn if a combination treatment of a hormonal intrauterine device (LNG-IUD), semaglutide, and a structured weight loss p…

Endometrial Atypical HyperplasiaEndometrial Atypical Hyperplasia/Endometrioid Intraepithelial NeoplasiaEndometrial Cancer Stage I+3 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

The Methodist Hospital Research InstituteNCT07820358

Observational

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

To assess the feasibility of an expedited referral process for the obese endometrial cancer or EIN patient from her gynecologic oncologist to the Brigham Cente…

Endometrial CarcinomaObesityEIN+2 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Dana-Farber Cancer InstituteNCT04839614

Phase 1

Window of Opportunity Trial of Fenofibrate in Patients With High-grade Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma

Normally, p53 helps prevent tumors from forming in the body. Early studies have shown that Fenofibrate, a cholesterol-lowering drug, can restore normal functio…

Cervical Intraepithelial NeoplasiaInvasive Cervical Cancer

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Lindsay Ferguson, MDNCT06191133

Observational

The Effectiveness of Screening Women With Lower Genital Tract Neoplasia or Cancers for Anal Cancer Precursors

The goal of this single arm trial is to prospectively evaluate screening methods for anal cancer precursors in HIV uninfected women with a history of lower gen…

Estimated

~$10 – $750

Actual pay is set by the research site.

Icahn School of Medicine at Mount SinaiNCT05217940

Phase 2

A Randomized, Window of Opportunity Trial of Tirzepatide in Women With Obesity and a Diagnosis of Endometrial Intra-epithelial Neoplasia (EIN) or Grade 1 Endometrial Cancer

The goal of this study is to determine the anti-proliferative effect of tirzepatide on the endometrium of patients with endometrial intra-epithelial neoplasia …

Endometrial CancerEndometrial Intraepithelial NeoplasiaGrade 1 Endometrial Endometrioid Carcinoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

UNC Lineberger Comprehensive Cancer CenterNCT07078838