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847 recruiting studies matching your filters

A Phase II Trial of Focal Ultrahypofractionated Stereotactic Radiation Therapy for the Treatment of Unifocal Prostate Cancer

Background: The current standard treatment of prostate cancer is either surgery or radiation. Typically, this includes either the removal or radiation of the …

Prostatic NeoplasmsProstate CancerProstate Adenocarcinoma

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT05616650

Phase 2

A Phase 2 Trial Investigating Decitabine in Combination With a JAK-Inhibitor as a Bridge to Allogeneic Hematopoietic Stem Cell Transplant in Patients With Accelerated/Blast Phase Myeloproliferative Neoplasms

This phase II trial studies how well decitabine with ruxolitinib, fedratinib, or pacritinib works before hematopoietic stem cell transplant in treating patient…

Acute Myeloid LeukemiaEssential ThrombocythemiaMyelodysplastic Syndrome+6 more

Estimated

~$10 – $6,250

University of WashingtonNCT04282187

Phase 3

A Phase 3, Randomized, Open-label, Multicenter Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) Maintenance Treatment With or Without Bevacizumab Versus Standard of Care in Participants With Newly Diagnosed Advanced Non-HRD Positive Ovarian Cancer Following First-line Platinum-based Chemotherapy (TroFuse-021/ENGOTov85/GOG-3102)

Researchers are looking for new ways to treat ovarian cancer (OC). Current treatment for OC may start with surgery to remove as much of the cancer as possible.…

Ovarian NeoplasmsOvarian Cancer

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT07318558

Observational

Personal Archetypes Toward Healing (PATH) Trial

This clinical trial tests the feasibility and effectiveness of a spiritual health intervention (Personal Archetypes Toward Healing Trial \[PATH\]) for improvin…

Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm

Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT07545291

ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE), a Case Collection Registry for 3D Breast Automated Ultrasound Using ATUSA System as Well as Other Breast Imaging Modalities.

AUDIBLE is a multi-site, clinical study conducted in the United States aimed at gathering data on 3D Automated Breast Ultrasound imaging using the iSono Health…

Breast CancerBenign Breast ConditionBreast Fibroadenoma+6 more

Estimated

~$10 – $1,050

iSono Health, Inc.NCT07505797

Phase 1

AN INTERVENTIONAL PHASE 1B/2 STUDY TO EVALUATE THE SAFETY AND EFFICACY OF PF-08634404 MONOTHERAPY AND IN COMBINATION WITH OTHER ANTICANCER AGENTS IN ADULT PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC RENAL CELL CARCINOMA

This study is testing a new medicine called PF-08634404 and how it works in adults with advanced Renal Cell Carcinoma (RCC)- a type of kidney cancer that is ei…

Carcinoma, Renal CellAdvanced Renal Cell CarcinomaRenal Cancer+10 more

A Phase 2, Multicenter, Double-Blind, Randomized, Controlled Trial of the Safety and Immunogenicity of a Self-Amplifying mRNA COVID-19 Vaccine in Adult Hematopoietic Cell Transplant Recipients

This phase IIb trial compares the effect of LUNAR-COV19 vaccine to Comirnaty vaccine in treating adult patients who have received a hematopoietic cell transpla…

Hematopoietic and Lymphatic System Neoplasm

Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT07390968

Phase 3

A Phase III, Multisite, Randomized, Double-Blind Trial of BNT327 in Combination With Chemotherapy Versus Placebo With Chemotherapy in Patients With Previously Untreated Locally Recurrent Inoperable or Metastatic TNBC Determined Ineligible for PD(L)1 Therapy Based on PD-L1 Negative Disease

This is a Phase III trial where participants will be randomized to two treatment groups, which means participants will be assigned by equal chance to a treatme…

Breast Neoplasms

Estimated

~$10 – $7,500

BioNTech SENCT07173751

Phase 1

LIGHTBEAM-U01 Substudy 01C: A Phase 1/2 Substudy to Evaluate the Safety and Efficacy of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors

Researchers are looking for new ways to treat children with hepatoblastoma or rhabdomyosarcoma (RMS) that has relapsed or is refractory: * Hepatoblastoma is a…

Malignant Neoplasm

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT06941272

Establishment of a National Biorepository to Advance Studies of Immune-Related Adverse Events

This study collects research data and samples from patients who experience immunotherapy side effects to store for use in future research studies. Studying res…

Hematopoietic and Lymphoid Cell NeoplasmImmune System DisorderMalignant Solid Neoplasm

Estimated

~$10 – $750

Alliance for Clinical Trials in OncologyNCT04242095

Observational

Impact of Treatment Intensity on Survival, Quality of Life, and Resource Utilization in Medically Less Fit Adults With Acute Myeloid Leukemia or High-Grade Myeloid Neoplasms: A Randomized Pilot Study

This clinical trial studies whether less fit adults with acute myeloid leukemia (AML) or myeloid neoplasms are willing to let a computer program decide (random…

Acute Leukemia of Ambiguous LineageAcute Myeloid LeukemiaMyeloid Neoplasm

Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT07094750

Phase 1

MK-5684-01A Substudy: A Phase 1/2 Umbrella Substudy of MK-5684-U01 Master Protocol to Evaluate the Safety and Efficacy of MK-5684-based Treatment Combinations or MK-5684 Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC)

Substudy 01A is part of a larger research study that is testing experimental treatments for metastatic castration-resistant prostate cancer (mCRPC). The larger…

Prostatic Neoplasms, Castration-Resistant

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT06353386