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Phase 1
A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
The primary objective of this Phase 1, open-label, dose-escalation, and exploratory study is to evaluate the safety and tolerability profile (establish the max…
Central Nervous System NeoplasmsGlioblastomaGliosarcoma, Adult+20 more
Jazz PharmaceuticalsNCT04541082
Phase 1
Phase 1 Trial of Engineered HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors
This study is a clinical trial to determine the safety of inoculating G207 (an experimental virus therapy) into a recurrent or refractory cerebellar brain tumo…
Neoplasms, BrainGlioblastoma MultiformeGlioblastoma of Cerebellum+30 more
M.D. Anderson Cancer CenterNCT03911388