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28 recruiting studies matching your filters
Phase 2
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)
This is a multi-arm phase II platform-basket screening study designed to test multiple experimental therapies simultaneously in patients with NF2-related schwa…
Neurofibromatosis Type 2Vestibular SchwannomaNon-vestibular Schwannoma+2 more
Estimated
~$10 – $7,500
Scott R. Plotkin, MD, PhDNCT04374305
Phase 1
A Phase 1/1b Open Label Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PAS-004, a MAPK/ERK Kinase 1/2 (MEK 1/2) Inhibitor, in Adult Participants With Neurofibromatosis Type 1 (NF1) With Symptomatic and Inoperable, Incompletely Resected, or Recurrent Plexiform Neurofibromas
The main purpose of this clinical trial is to test PAS-004 in people with at least one symptomatic plexiform neurofibroma due to Neurofibromatosis Type 1 (NF1)…
NF1 MutationNeurofibroma PlexiformNeurofibroma, Plexiform+2 more
Estimated
~$10 – $8,750
Pasithea Therapeutics Corp.NCT06961565
Investigation Into the Natural History and Metabolic and Molecular Basis of RASopathies.
The RASopathies are a group of developmental disorders caused by genetic changes in the genes that compose the Ras/mitogen activated protein kinase (MAPK) path…
RAS MutationNeurofibromatosis 1Noonan Syndrome+11 more
Estimated
~$10 – $675
Children's Hospital Medical Center, CincinnatiNCT04395495
Neurofibromatosis (NF) Registry Portal Funded by Children's Tumor Foundation
The NF Registry is a database of patient-reported symptoms, treatments, and experiences with their neurofibromatosis disease. It is a contact registry to relay…
Neurofibromatosis 1Neurofibromatosis 2Schwannomatosis
Estimated
~$10 – $750
The Children's Tumor FoundationNCT01885767