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16 recruiting studies matching your filters
Observational Trial of Liquid Biopsy for Malignant Peripheral Nerve Sheath Tumor (MPNST) Among Participants With Neurofibromatosis Type 1
The goal of this observational study is to determine if a liquid biopsy (i.e. blood test) is an effective clinical tool for monitoring the development of malig…
Neurofibromatosis Type 1Neurofibromatosis 1Plexiform Neurofibroma+4 more
Estimated
~$10 – $1,125
David MillerNCT06515860
Phase 2
Efficacy of Mirdametinib Alone or Combination With Radiotherapy for Germline and Sporadic NF1-Altered High-Grade Glioma
This is a phase 2, open label, parallel multi-arm study of mirdametinib in combination with radiation in participants with recurrent sporadic glioblastoma (GBM…
Neurofibromatosis 1 (NF1)
Estimated
~$10 – $6,250
University of Alabama at BirminghamNCT07521657
Investigation Into the Natural History and Metabolic and Molecular Basis of RASopathies.
The RASopathies are a group of developmental disorders caused by genetic changes in the genes that compose the Ras/mitogen activated protein kinase (MAPK) path…
RAS MutationNeurofibromatosis 1Noonan Syndrome+11 more
Estimated
~$10 – $675
Children's Hospital Medical Center, CincinnatiNCT04395495
Neurofibromatosis (NF) Registry Portal Funded by Children's Tumor Foundation
The NF Registry is a database of patient-reported symptoms, treatments, and experiences with their neurofibromatosis disease. It is a contact registry to relay…
Neurofibromatosis 1Neurofibromatosis 2Schwannomatosis
Estimated
~$10 – $750
The Children's Tumor FoundationNCT01885767