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Observational
An Exercise Training Intervention for Depressive Symptoms in Youth With MS: A Randomized Controlled Feasibility Trial
This multi-center, randomized controlled feasibility trial will assess a 20-week home-based exercise intervention in youth with Multiple Sclerosis (MS). The go…
Neuroinflammatory DiseasesMultiple Sclerosis
The Hospital for Sick ChildrenNCT06870968
Phase 1
Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy: A Pilot Study
Background: Multiple sclerosis (MS) and progressive multifocal leukoencephalopathy (PML) are disorders that affect the central nervous system (CNS). The CNS i…
Progressive Multifocal LeukoencephalopathyMultiple SclerosisOther Neuroinflammatory Diseases With BBB Leakage
National Institute of Neurological Disorders and Stroke (NINDS)NCT05849467