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42 recruiting studies matching your filters

Development of a Novel Soluble Epoxide Hydrolase Inhibitor as a Strategy for Treating Neuropathic Pain in Patients With SCI

The goal of this clinical trial is to evaluate safety and tolerability of multiple oral doses of EC5026 in male and female patients with neuropathic pain due t…

Spinal Cord InjuriesNeuropathic PainDegenerative Disc Disease+2 more

Estimated

~$10 – $8,750

EicOsis Human Health Inc.NCT06438471

Phase 2

Randomized, Placebo-Controlled, Phase 2 Clinical Trial to Evaluate LY4065967 for the Treatment of Diabetic Peripheral Neuropathic Pain

The purpose of this study is to test the safety and efficacy of study drug LY4065967 for the treatment of diabetic peripheral neuropathic pain (DPNP). This tri…

Diabetic Peripheral Neuropathic Pain

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07285018

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Mana…

Neuropathic Pain

Estimated

~$10 – $750

Indiana UniversityNCT06420141

Observational

Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).

This observational, prospective data collection is designed to evaluate the efficacy of CL-SCS therapy in real-world patients suffering from chronic pain.

PainChronic PainNeuropathic Pain

Estimated

~$10 – $5,625

Saint Francis HospitalNCT06246526

Phase 1

A Phase 1, First-in-human, Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASCT-83 Subcutaneous Injection in Healthy Adults

The goal of this clinical trial is to learn if ASCT-83 is safe and well-tolerated and measure how ASCT-83 is absorbed, distributed, and eliminated from the bod…

Neuropathic Pain

Estimated

~$10 – $8,750

Alcamena Stem Cell TherapeuticsNCT07363395

Phase 3

A Phase 3, Randomized, Double-blind, Placebo- and Active-Controlled Study of the Efficacy and Safety of Suzetrigine in Subjects With Pain Associated With Diabetic Peripheral Neuropathy

The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabetic periphe…

Diabetic Peripheral Neuropathic Pain

Estimated

~$10 – $8,750

Vertex Pharmaceuticals IncorporatedNCT06628908

Brain Connectivity Changes With Spinal Cord Stimulation Treatment of Chronic Pain: A Resting State NIRS/EEG Study

This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function. The investigators will use…

Neuropathic Pain

Estimated

~$10 – $675

VA Office of Research and DevelopmentNCT05811312

Observational

tACS Brain Neuromodulation for Sensory and Motor Recovery After Neurological Impairments

The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for neuropathic pain managem…

Neuropathic Pain Management

Estimated

~$10 – $6,250

The University of Texas Health Science Center, HoustonNCT06029075

Phase 2

A Phase 2, Randomized, Double-blind, Active-controlled, Dose-ranging, Parallel-design Study of the Efficacy and Safety of Oral VX-993 in Subjects With Pain Associated With Diabetic Peripheral Neuropathy

The purpose of this study is to evaluate the efficacy, safety, and tolerability of VX-993 in participants with pain associated with Diabetic Peripheral Neuropa…

Diabetic Peripheral Neuropathic Pain

Estimated

~$10 – $8,750

Vertex Pharmaceuticals IncorporatedNCT06619860

Phase 1

A Multicenter Phase 1 / 2 Double-blind, Randomized, Sham-controlled Dose Escalation Study to Determine Safety and Tolerability of Single Dose Intrathecal ST-503 Gene Therapy for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)

This research is being done to study a possible treatment for refractory pain due to small fiber neuropathy (SFN). ST-503 is intended to deliver a modified co…

Chronic Neuropathic Pain

Estimated

~$10 – $8,750

Sangamo TherapeuticsNCT06980948

Phase 2

Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain

Chronic neuropathic pain (CNP) is disabling. Research on frontline treatments for CNP, shows inconsistent outcomes and dissatisfaction among Veterans. Veterans…

Neuropathic PainPeripheral Neuropathic Pain

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT05351801

Observational

Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury

The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with incomplete spinal cord inj…

Spinal Cord InjuriesNeuropathic Pain

Estimated

~$10 – $6,250

Texas A&M UniversityNCT06330181