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Phase 2
Investigating Efficacious E-Cigarette Interventions and Cessation Effects on Cancer-Related Biomarkers: A Randomized Trial of Varenicline in Adults
This is randomized, placebo-controlled clinical trial in treatment-seeking adults who report regular e-cigarette use to test the hypothesis that varenicline is…
E-cigarette UseVapingNicotine Dependence
Estimated
~$10 – $6,250
Yale UniversityNCT07040566
Observational
Evaluating The Effects Of E-cigarettes Versus Oral Nicotine Pouches and Product Constituents (Menthol Flavor, Nicotine Concentration) On Adult Cigarette Smoking and Addiction
The study will recruit an anticipated 256 adults who currently smoke cigarettes and report a willingness to try switching to alternative, non-combustible produ…
SmokingSmoking BehaviorsNicotine Dependence
Estimated
~$10 – $6,250
Yale UniversityNCT06077240
Observational
Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches as a Harm Reducing Substitute for Combustible Cigarettes - (Pack2Pouch)
Tobacco-free oral nicotine pouches (such as Zyn brand) are a less harmful alternative to cigarette smoking. Pouches, however, contain nicotine, and addictive s…
Cigarette SmokingNicotine DependenceSmoking Cessation
Estimated
~$10 – $6,250
Medical University of South CarolinaNCT06678789
Observational
E-cigarette Prevention and Emotion Regulation: Virtual Reality Intervention for Adolescents
This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver preventi…
E-cigarette Use/Vaping PreventionNicotine Dependence PreventionAdolescent Mental Health
Estimated
~$10 – $6,250
Yale UniversityNCT07460622