The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient f…

Metabolic DisordersHematologic, Immune, or Bone Marrow DisordersHemoglobinopathies+1 more

~Estimated

~$10 – $6,250

Washington University School of MedicineNCT00920972

Phase 1

A Phase I/II Trial of Reduced Intensity Conditioning and Familial HLA-Mismatched Bone Marrow Transplantation in Children With Non-Malignant Disorders

This study is designed to estimate the efficacy and toxicity of familial HLA mismatched bone marrow transplants in patients with non-malignant disease who are …

Severe Sickle Cell DiseaseBone Marrow Failure SyndromesMetabolic Disorders+3 more

~Estimated

~$10 – $6,250

Washington University School of MedicineNCT03128996