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Phase 1
A Study of Hematopoietic Stem Cell Transplantation (HSCT) in Non-Malignant Disease Using a Reduced-Intensity Preparatory Regime
The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient f…
Metabolic DisordersHematologic, Immune, or Bone Marrow DisordersHemoglobinopathies+1 more
Washington University School of MedicineNCT00920972
Phase 1
A Phase I/II Trial of Reduced Intensity Conditioning and Familial HLA-Mismatched Bone Marrow Transplantation in Children With Non-Malignant Disorders
This study is designed to estimate the efficacy and toxicity of familial HLA mismatched bone marrow transplants in patients with non-malignant disease who are …
Severe Sickle Cell DiseaseBone Marrow Failure SyndromesMetabolic Disorders+3 more
Washington University School of MedicineNCT03128996