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322 recruiting studies matching your filters

Biospecimen Procurement for the Study of Head and Neck Disorders

Background: Researchers want to learn more about head and neck disorders. Understanding these disorders could help them find better treatments. To do this, th…

Hearing DisorderOral Mucosal DiseasePharyngeal Neoplasm+2 more

Estimated

~$10 – $675

National Cancer Institute (NCI)NCT03429036

Phase 2

MC230719 Window Of Opportunity Study Of GI-102 In Patients With Recurrent High-Grade Glioblastoma

This phase II trial compares the effect of GI-102 alone and in combination with pembrolizumab given before surgery in treating patients with IDH wildtype gliob…

Glioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more

Estimated

~$10 – $6,250

Mayo ClinicNCT07301268

Phase 3

A Randomized Phase III Trial of Doxorubicin + Pembrolizumab Versus Doxorubicin Alone for the Treatment of Dedifferentiated Liposarcoma (DDLPS), Undifferentiated Pleomorphic Sarcoma (UPS) and Related Poorly Differentiated Sarcomas

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patie…

Metastatic Dedifferentiated LiposarcomaMetastatic Undifferentiated Pleomorphic SarcomaStage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8+3 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06422806

Phase 2

A Phase II Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma

A phase 2 study assessing the efficacy of all-trans retinoic acid (ATRA) and Cemiplimab in patients with metastatic/locally advanced - unresectable leiomyosarc…

LeiomyosarcomaSarcoma

Estimated

~$10 – $7,500

Gabriel TinocoNCT06528769

Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders

Background: Trisomy 8 mosaicism is a genetic disorder that can increase inflammation in the body. Symptoms include fevers; sores or ulcers in the mouth, diges…

Trisomy 8 MosaicismTrisomy 8 Associated Autoinflammatory DiseaseMucosal Ulcerations

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT07683104

Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis

Background: \- Vasculitis is a group of diseases that inflame and damage blood vessels and tissue. It can cause many medical problems. Few tests can diagnose …

Takayasu's ArteritisGiant Cell ArteritisPolyarteritis Nodosa+2 more

Estimated

~$10 – $675

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)NCT02257866

Phase 2

A Phase IIb Randomized, Double-blind, Placebo-controlled, Parallel, Multidose Study to Evaluate the Efficacy, Safety, and PK of AZD0292 in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

AZD0292 is a bispecific IgG1k mAb being evaluated for the prevention of exacerbations in bronchiectasis patients chronically colonized with PsA.

Bronchiectasis With Pseudomonas Aeruginosa Colonization

Estimated

~$10 – $7,500

AstraZenecaNCT07088926

Phase 1

Phase 1b Trial of Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery in Patients With Pulmonary Recurrence of Osteosarcoma

This study aims to determine the safety and tolerability of combined Atezolizumab, stereotactic body radiation therapy (SBRT), and surgical resection of pulmon…

OsteosarcomaPulmonary Recurrence of Osteosarcoma

Estimated

~$10 – $6,250

Emory UniversityNCT06492954

Phase 2

MC1963 Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for Patients With Advanced Stage Ovarian Cancer: A Phase II Double-Blind Randomized Clinical Trial (FAROUT)

This phase II trial compares the effect of folate receptor alpha dendritic cells (FRαDCs) to placebo in treating patients with stage III or IV ovarian, fallopi…

Advanced Fallopian Tube CarcinomaAdvanced Fallopian Tube High Grade Serous AdenocarcinomaAdvanced Ovarian Carcinoma+15 more

Estimated

~$10 – $6,250

Phase 2

A Phase 1/2 Study of DS-8201a (NSC# 807708) in Children, Adolescents, or Young Adults With Recurrent Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

This phase I/II trial studies the effects of trastuzumab deruxtecan (DS-8201a) in treating patients with osteosarcoma, Wilms tumor (WT) or desmoplastic small r…

Desmoplastic Small Round Cell TumorOsteosarcomaRecurrent Desmoplastic Small Round Cell Tumor+5 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT04616560

Observational

Evaluation of F&P Mask, US, 2026

This clinical investigation is designed to validate and confirm the overall performance, safety, usability, reliability, and acceptability of the F\&P mask in …

Chronic Respiratory ConditionsObstructive Sleep Apnea (OSA)

Estimated

~$10 – $7,500

Fisher and Paykel HealthcareNCT07847814

Phase 1

Phase I/II Study to Evaluate the Feasibility and Efficacy of Sequential Abemaciclib and Gemcitabine Treatment in Patients With Retinoblastoma (Rb)+ Sarcomas

This phase I/II trial tests the side effects and best dose of abemaciclib when added to gemcitabine and compares the effectiveness of that treatment to the usu…

Advanced Dedifferentiated LiposarcomaAdvanced LeiomyosarcomaAdvanced Soft Tissue Sarcoma+5 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06498648