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Observational
Effects of Pistachio Snacking on Metabolic Flexibility in Healthy Overweight and Obese Adults
The purpose of this study is to evaluate the effects of pistachio snacking on metabolic flexibility (at rest, during exercise, and in post-exercise recovery) i…
Overweight (BMI > 25)Obese But Otherwise Healthy ParticipantsOverweight or Obese+4 more
University of South CarolinaNCT07340125
Observational
Fructose Metabolism Effects on the Liver: Unraveling the Role of Defective Intestinal GNG in Individuals With Obesity
This study will test the hypothesis that within a defined range of fructose intake, the ability to convert fructose to glucose (via gluconeogenesis) in the sma…
Healthy ParticipantsObese But Otherwise Healthy Participants
Touro University, CaliforniaNCT07209202
Phase 1
A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Dose-Range Finding Study of the Efficacy, Safety, and Pharmacokinetics of CRB-913 in Participants With Obesity With a Single Cohort Open-label Exploratory Pharmacokinetic Lead-In
This study will assess the safety of the investigational drug CRB-913 and how it is processed in the body. The study has two parts: Part 1 will measure drug l…
Obese But Otherwise Healthy Participants
Corbus Pharmaceuticals Inc.NCT07310901