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Phase 4
A Single-institution, Parallel, Double-blinded, Randomized Study Assessing the Safety and Efficacy of Transdermal Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery
Addictive full-agonist opioids, like oxycodone and hydrocodone, are often used to treat pain after surgery. However, these full-agonist opioids can be very add…
Pain, PostoperativeAnkle Fracture SurgeryOpioid Use Disorder+2 more
Jenna-Leigh WilsonNCT06949826
Phase 1
Evaluation of the Safety and Effects of Psychoactive Substances in People With Past Opioid Use
The purpose of this study is to understand how kratom affects people. In this study, kratom will be compared with another substance and a placebo (an inactive …
Opioid UseSubstance Use DisordersOpioid Analgesia
Christopher D. VerricoNCT07218549