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Observational
Onsite PTSD Treatment to Improve MOUD Outcomes: Open Pilot Trial of Stakeholder-engaged Adapted Cognitive Processing Therapy
The goal of this open pilot trial is to learn if an adapted version of Cognitive Processing Therapy (CPT), delivered through telehealth, can treat posttraumati…
Posttraumatic Stress Disorder (PTSD)Opioid Use Disorder
The City College of New YorkNCT06872164
Phase 3
ED-Initiated Standard Versus High Dose Buprenorphine Induction
This study is a multisite double-blind, double-dummy, randomized clinical trial enrolling ED patients with untreated moderate to severe opioid use disorder (OU…
Opioid Use Disorder
Yale UniversityNCT06494904
Phase 1
Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
This study will examine the synaptotrophic effects of psilocybin among medically healthy, detoxified OUD subjects. Eligible OUD participants will undergo pre- …
Opioid Use Disorder
Yale UniversityNCT06160284