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235 recruiting studies matching your filters

Research to Foster an Opioid Use Disorder Treatment System Patients Can Count On: Project 2 - Producing Outcome Measures for OTP Quality Improvement

This study tests ways to help opioid treatment programs (OTPs) keep patients in care. Staying on methadone or buprenorphine is linked to better outcomes, yet m…

Opioid Use Disorder

Estimated

~$10 – $7,500

RTI InternationalNCT07214389

Observational

Empowering Support Persons to Enhance the Recovery Capital of Postpartum Women With Opioid Use Disorder - R61 Phase

We are studying whether training an identified support person and providing patient navigation (i.e. a peer recovery specialist assisting you with finding the …

Opioid Use Disorder

Estimated

~$10 – $8,750

Friends Research Institute, Inc.NCT07787039

Phase 4

Optimizing Long-Acting Pre-Exposure Prophylaxis and Medications for Opioid Use Disorder Interventions in Carceral Settings

The investigators plan to conduct an R61/33 hybrid type 2 implementation-effectiveness trial that includes 1) a one-year exploratory R61 phase that will enable…

HIV InfectionsOpioid Use DisorderIncarceration; Lens

Estimated

~$10 – $6,250

Duke UniversityNCT06854029

Observational

The Vira Platform: A Contextually Triggered Just-in-Time Adaptive Intervention for Opioid Use Disorder

Many patients stop medication-based treatments for Opioid Use Disorder (OUD) prematurely, placing them at increased risk for overdose and death. Providing targ…

Opioid Use DisordermHealthPeer Support

Estimated

~$10 – $6,250

Rhode Island HospitalNCT07778394

Phase 2

Ketone Supplementation for Opioid Craving and Withdrawal

The goal of this clinical trial is to learn if ketone supplementation (KS) works to reduce craving for opioids for adults with opioid use disorder (OUD) underg…

Opioid Use Disorder

Estimated

~$10 – $6,250

University of Maryland, BaltimoreNCT07128524

Observational

CTN-0156: Pilot Development and Evaluation of a Patient Decision Aid for Emergency Department Initiated Buprenorphine

This study aims to develop and pilot test a patient decision aid (PtDA) for emergency department (ED)-initiated buprenorphine treatment for opioid use disorder…

Opioid Use Disorder

Estimated

~$10 – $6,250

Medical University of South CarolinaNCT07278518

Phase 2

Evaluating a Mechanistically-Supported Pharmacotherapy to Treat Opioid Withdrawal

The investigators propose a rigorous, Phase II, three-group, placebo-controlled double-blind randomized controlled trial (RCT) to evaluate the efficacy of busp…

Opioid Use DisorderOpioid WithdrawalOpioid Craving+1 more

Estimated

~$10 – $6,250

University of Maryland, BaltimoreNCT05511909

Observational

A Pilot Randomized Controlled Trial to Improve Outpatient Initiation of Medication for Opioid Use Disorder (MOUD) Following Hospitalization: The TRTME (Tailored Overdose Risk Feedback, Testimonials for MOUD Treatment, and Education on MOUD and Opioid Overdose) Trial

The primary objective of this study is to evaluate the ability of TRTME to increase initiation of MOUD outpatient treatment and MOUD knowledge in hospitalized …

Opioid Use DisorderOpioid Use Disorder, ModerateOpioid Use Disorder, Severe

Estimated

~$10 – $7,500

T. John Winhusen, PhDNCT07780097

Phase 1

Cannabis and Opioid Use Disorder, Study 2

This inpatient study enrolls healthy individuals who have opioid use disorder. Participants live at the University of Kentucky Hospital for approx. 6 weeks. Du…

Opioid Use DisordersCannabis Use

Estimated

~$10 – $6,250

University of KentuckyNCT07661446

Phase 1

Impact of Cannabis on Opioid Self-Administration

The study will enroll participants with opioid use disorder and participants will reside at the University of Kentucky Hospital for this 6-week inpatient trial…

Opioid Use DisorderCannabis Use

Estimated

~$10 – $7,500

Shanna Babalonis, PhDNCT07668635

Observational

Early Detection of Neonatal Opioid Withdrawal Syndrome Using a Novel Cerebral Monitor.

This study will use a new device to measure blood flow and oxygen levels in the brains of newborn infants who have had exposure to opioid medications in the wo…

Neonatal Opioid WithdrawalNeonatal Opioid Withdrawal SyndromeOpioid Use Disorder+1 more

Estimated

~$10 – $6,250

Indiana UniversityNCT07610746

Observational

Real-world Assessment of Social Functioning During OUD Treatment: Integrating Reports From Patients and Their Concerned Significant Others

Problems with social functioning are core to opioid use disorder (OUD), though specific, modifiable social functioning targets and how they relate to OUD treat…

Opioid Use Disorder

Estimated

~$10 – $6,250

Medical University of South CarolinaNCT07044466