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Phase 1
Safety and Chemopreventive Efficacy of Fenretinide Mucoadhesive System in Subjects With Premalignant Oral Intraepithelial Neoplasia (OIN) Lesions: In Conjunction With Pharmacokinetic Assessment in Healthy Subjects.
The goal of this clinical trial is to determine the effect of a mucoadhesive system that releases the vitamin A derivative, fenretinide (FMS), on precancerous …
Oral LeukoplakiaOral Dysplasia
Ohio State UniversityNCT07149220
Phase 1
Topical Imiquimod for the Treatment of Oral Dysplastic Lesions With Clinical and Histologic Assessments
The goal of this clinical trial is to determine the effectiveness of imiquimod in treating oral dysplasia in adult patients. Imiquimod 5% cream could be a safe…
Oral DysplasiaLeukoplakia OralLeukoplakia
University of Southern CaliforniaNCT07210775