This phase II pilot trial studies how well pembrolizumab works in treating leukoplakia. Monoclonal antibodies, such as pembrolizumab, may interfere with the ab…

ErythroleukoplakiaLeukoplakiaVerrucous Oral Leukoplakia

~Estimated

~$10 – $6,250

Jonsson Comprehensive Cancer CenterNCT03603223

Phase 2

Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

This is a Phase IIa oral cavity leukoplakia study of pioglitazone 15mg and metformin 500mg BID for 12 weeks. The primary objective is to determine the clinical…

Oral Leukoplakia

~Estimated

~$10 – $6,250

University of MinnesotaNCT05727761