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Phase 2
Neurofunctional Phenotyping to Investigate the Role of the Orexin System at the Intersection of Opioid Use Disorder and Insomnia Among Women and Men Receiving Buprenorphine
The goal of this clinical trial is to learn about how certain medications used to treat insomnia (e.g., Lemborexant) impact sleep, mood, and behavior in men an…
Opioid Use DisorderOpioid UseInsomnia+1 more
Virginia Commonwealth UniversityNCT06981195
Phase 4
Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients With Cannabis Use Disorder
The goal of this study is to observe the impact of suvorexant, sold as BELSOMRA, on brain activity of people who frequently use cannabis. Suvorexant is an FDA-…
Cue-reactivityCannabis Use DisorderFunctional MRI+1 more
Massachusetts General HospitalNCT06584942