The long-term goal is to test the clinical efficacy of senolytic therapies to reduce progression to and severity of sepsis in older patients. The central hypot…

SepsisAcute InfectionOrgan Failure

~Estimated

~$10 – $6,250

University of MinnesotaNCT05758246

Alveolar Dead Space as Predictor of Multi-organ Failure and Mortality in Medical Intensive Care Patients With Sepsis Requiring Mechanical Ventilation

This is an observational study to understand the changes in alveolar dead space in medical critically ill patients with severe infection (severe sepsis) requir…

SepsisSevere SepsisSeptic Shock+1 more

~Estimated

~$10 – $750

The University of Texas Health Science Center, HoustonNCT01315782

Phase 1

Prospective Evaluation of a Point-of-Care Artificial Intelligence Model in Critical Care Outcomes

This is a prospective, unmasked, randomized, multicenter clinical trial evaluating the impact of point-of-care large language model (LLM)-based decision suppor…

Critical IllnessSepsisAcute Respiratory Failure (ARF)+4 more

~Estimated

~$10 – $7,500

MetroWest Artificial Intelligence Research WorkgroupNCT07293078