The purpose of this study is to examine the impact of new cancer genetic counseling models that aim to increase patient engagement with the genetics team. To d…

BRCA1 MutationPOLD1 Gene MutationCDKN2A Mutation+19 more

~Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT05420064

Phase 1

Combination Therapy of Niraparib and Irinotecan in Cancers With Mutations in DNA Repair Genes

The purpose of this phase 1 clinical trials is to determine whether niraparib (a Poly (ADP-ribose) polymerase inhibitor (PARPi)) can be safely combined with ir…

Metastatic Solid TumorBRCA1 MutationBRCA2 Mutation+2 more

~Estimated

~$10 – $5,625

University of California, San FranciscoNCT05694715

Phase 1

SHARON: Study of Metastatic Cancers in Patients Using Autologous Stems Cells and Potentiated Redox Cycling to Overcome Drug Resistance to Nitrogen Mustard Derivatives

The clinical trial is a phase 1, single-arm trial that will evaluate the safety of the investigational treatment on metastatic pancreatic cancer and metastatic…

Pancreatic Adenocarcinoma MetastaticBRCA1 MutationBRCA2 Mutation+17 more

~Estimated

~$10 – $8,750

General Oncology, Inc.

NCT04150042