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Mechanisms of Stimulation for Pain Alleviation
This is a mechanistic randomized controlled trial of patients with chronic neuropathic pain (CNP) in the lower back, pelvis, and lower extremities, randomized …
Pilot Study of Banana Leaves as a Primary Wound Dressing for Partial Thickness Burn Wounds
This study plans to look at the benefits of banana leaves as a primary burn wound dressing. Study patients will be compared to historical patients
Brown Adipose Tissue Activation by Spinal Cord Stimulation
The objective of this study is to investigate and utilize spinal cord stimulation (SCS) as an effective approach to eliciting weight loss and potentially allev…
Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell Disease
This research is being conducted to see if using an injectable contraception, Depot Medroxyprogesterone Acetate (Depo-Provera), can reduce the pain experienced…
Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain - Phase II
The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and …
Post Market Clinical Follow up Study to Provide Safety, Performance and Clinical Benefits Data of the Taperloc Complete Stems
The objective of this consecutive series PMCF study is to collect data confirming safety, performance, and clinical benefits of the Taperloc Complete stems whe…
Novel Cellular Therapy for the Treatment of Pain Associated With Chronic Pancreatitis
The goal of this clinical trial is to test whether adult stem cells, called mesenchymal stem cells (MSCs) collected from the patient's bone marrow can help red…
Development of a Parent Training Intervention for Pediatric Patients With Pain
The primary objective is to assess the feasibility and acceptability of a group-based parent training intervention for parents of youth with chronic pain. Seco…
Neural Mechanisms of Light Driven Analgesia
The goal of this study will be to understand the biological mechanisms that are responsible to light-driven analgesia. Light presented to the retina has been s…
Utilization of Transcutaneous Electrical Nerve Stimulation (TENS) Unit for Analgesia During IUD Insertion: A Prospective Cohort Study
Subjects will be screened over the phone or in Tufts GYN clinic for participation in the study. If eligible and interested in participating, written informed c…
Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat Pain
The goal of this research study is to find out how well oxytocin works to reduce pain. Oxytocin will be given intravenously (IV) and as a nasal spray. The stud…
Neural and Psychological Mechanisms of Pain Perception
Background: \- Painful stimuli cause changes in a network of brain regions called the "Pain Matrix." But most of these regions respond to many other stimuli, …