Browse Studies — Arctuva

Phase 1

A Phase 1 Dose-Escalation and Expansion Study Evaluating the Safety, Efficacy, and Pharmacokinetics of EVOLVE104 in Subjects With Advanced Urothelial and Squamous Cell Carcinomas

The goal of this study is to evaluate the safety and effectiveness of EVOLVE104 in participants with advanced urothelial and squamous cell carcinomas who have …

Bladder CancerSquamous Cell Carcinoma of the LungEsophageal Squamous Cell Carcinoma+8 more

Estimated

~$10 – $8,750

EvolveImmune United, IncNCT07217171

Phase 1

A Feasibility Study of E7 TCR-T Cell Induction Therapy for Locoregionally Advanced HPV-Associated Cancers

The goal of this study is to determine the feasibility of administration of a single dose of E7 TCR-T cells as induction therapy prior to definitive treatment …

HPV-Associated Cervical CarcinomaHPV-Related CarcinomaHPV-Related Malignancy+14 more

Estimated

~$10 – $7,500

Christian HinrichsNCT05639972

Phase 2

A Phase II Trial of T Cell Receptor Gene Therapy Targeting Human Papillomavirus ( HPV) 16 E7 for HPV-Associated Cancers

This is a phase II clinical trial to assess the clinical activity of immunotherapy with E7 TCR-T cells for metastatic HPV-associated cancers. HPV-associated ca…

Cervical CancerThroat CancerOropharynx Cancer+18 more

Estimated

~$10 – $7,500

Christian Hinrichs

Phase 2

Phase II Study of Enfortumab Vedotin Treatment for Metastatic Squamous Cell Carcinoma of the Penis

This phase II trial tests how well enfortumab vedotin works for treating patients with squamous cell carcinoma of the penis that has spread to other places in …

Metastatic Penile Squamous Cell CarcinomaStage III Penile Cancer AJCC v8Stage IV Penile Cancer AJCC v8+1 more

Estimated

~$10 – $6,250

Mayo ClinicNCT06104618