To find the recommended doses of lisaftoclax and olverembatinib that can be given in combination with decitabine to participants with advanced CML and Ph+ AML.

Advanced Chronic Myeloid LeukemiaPhiladelphia Chromosome-Positive Acute Myeloid Leukemia

~Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT06401603

Phase 1

Phase I/II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

To learn if the combination of blinatumomab and asciminib can help to control Ph+ ALL.

Philadelphia Chromosome-PositiveAcute Lymphoblastic Leukemia

~Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT06308588