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Observational
A Study to Evaluate the Efficacy of Pleural Space Saline Irrigation in Addition to Standard Intrapleural Thrombolytic Therapy in the Management of Empyema/Complicated Parapneumonic Effusion
The purpose of this study is to see if there is any benefit in adding saline irrigation through a chest tube to the standard course of treatment for people dia…
Pleural Infection
Mayo ClinicNCT06434324
Phase 4
Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema (ONLY ONCE)
The goal of this clinical trial is to find out if giving certain medications once a day works just as well as giving them twice a day to treat infections aroun…
Pleural Infection BacterialPleural InfectionsPleural Infections and Inflammations+5 more
University of North Carolina, Chapel HillNCT07095361
Observational
Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas
Infections of the pleural space are common, and patients require antibiotics and chest drain placement to evacuate the chest from the infected fluid. Chest dra…
Empyema, PleuralPleural Infection
Vanderbilt University Medical CenterNCT06427538