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3 recruiting studies matching your filters
Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)
Background: People with neurofibromatosis 1 (NF1) who have plexiform neurofibromas (pNFs) can have pain that affects their daily lives. This study aims to imp…
Neurofibromatosis 1Plexiform Neurofibromas
Estimated
~$10 – $675
National Cancer Institute (NCI)NCT02544022
Observational Trial of Liquid Biopsy for Malignant Peripheral Nerve Sheath Tumor (MPNST) Among Participants With Neurofibromatosis Type 1
The goal of this observational study is to determine if a liquid biopsy (i.e. blood test) is an effective clinical tool for monitoring the development of malig…
Neurofibromatosis Type 1Neurofibromatosis 1Plexiform Neurofibroma+4 more
Estimated
~$10 – $1,125
David MillerNCT06515860
Phase 1
A Phase 1/1b Open Label Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PAS-004, a MAPK/ERK Kinase 1/2 (MEK 1/2) Inhibitor, in Adult Participants With Neurofibromatosis Type 1 (NF1) With Symptomatic and Inoperable, Incompletely Resected, or Recurrent Plexiform Neurofibromas
The main purpose of this clinical trial is to test PAS-004 in people with at least one symptomatic plexiform neurofibroma due to Neurofibromatosis Type 1 (NF1)…
NF1 MutationNeurofibroma PlexiformNeurofibroma, Plexiform+2 more
Estimated
~$10 – $8,750
Pasithea Therapeutics Corp.NCT06961565