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Phase 2
A Pilot Randomized Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)
Amyotrophic lateral sclerosis (ALS) is a disease that causes weakness of the muscles of the body. The disease can eventually lead to severe breathing problems,…
Amyotrophic Lateral Sclerosis (ALS)Chronic Respiratory FailureNeuromuscular Disease Patients+7 more
University of PennsylvaniaNCT07071935
Observational
Comparing Two Multicomponent Strategies To Promote Supraglottic Airway Implementation During Neonatal Resuscitation
This is a hybrid type 3 effectiveness-implementation parallel cluster randomized superiority trial designed to compare two strategies to promote early supraglo…
Neonatal ResuscitationDelivery Room ResuscitationPositive Pressure Ventilation+4 more
Children's Hospital of PhiladelphiaNCT07150923
Observational
Supraglottic Airway Interface for Positive Pressure Ventilation During Delivery Room Resuscitation of Premature Infants: A Pilot Feasibility Trial
The goal of this single-arm intervention trial is to learn whether using a supraglottic airway (SA) as the primary interface for positive pressure ventilation …
Respiratory FailurePremature NeonatesDelivery Room Resuscitation+5 more
University of PennsylvaniaNCT07419438