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43 recruiting studies matching your filters

Optimal Maneuver to Reduce Postoperative Pain Following Elective Laparoscopic Surgeries

Laparoscopic surgery has revolutionized surgical care by reducing morbidity and improving post operative recovery. Laparoscopic surgery involves the use of car…

Laparoscopic SurgeryPost Operative Pain, AcutePneumoperitoneum

Estimated

~$10 – $6,250

Henry Ford Health SystemNCT07583433

Phase 4

Suzetrigine vs. Standard Care Rescue Medication in TKA Patients: A Matched Cohort Study

The purpose of this research is to see if a person having an outpatient total knee replacement will have a difference in their pain and the amount of pain medi…

Knee Arthroplasty, TotalPost Operative Pain, AcuteOpioid Consumption, Postoperative

Estimated

~$10 – $7,500

Endeavor HealthNCT07796152

Phase 4

The Impact of Perioperative Lidocaine Infusions on Enhanced Recovery After Non-Cardiac Surgery (IMPALA ERAS)

The goal of this single-center, pragmatic, randomized, blinded, placebo-controlled trial is to evaluate the impact of intravenous (IV) lidocaine within the exi…

PainPost Operative AnalgesiaOpioid Consumption, Postoperative

Estimated

~$10 – $6,250

Vanderbilt University Medical CenterNCT07224711

Phase 3

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2 - A Continuation of the Multicenter Randomized Control Trial SEXTANT 1

The PRCT evaluates infection outcomes as well as fracture and antibiotic-related complications to include the emergence of resistant bacteria associated with t…

Post Operative Surgical Site Infection

Estimated

~$10 – $7,500

Major Extremity Trauma Research ConsortiumNCT04678154

Phase 1

Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy

The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Expa…

Post Operative Pain

Estimated

~$10 – $6,250

Texas Tech University Health Sciences CenterNCT06349772

Phase 3

A Multicenter, Double-blind, Randomized, Parallel Group, Active-controlled, Dose-ranging Study to Assess Efficacy, Safety, and Pharmacokinetics of Combogesic® 325 in Adolescent Patients (Aged 12 to Less Than 18 Years) With Moderate to Severe Postoperative Pain Associated With Orthopedic Surgery

Combogesic® 325 contains a combination of ibuprofen and acetaminophen. The purpose of this study is to compare the pain relief effects of Combogesic® 325mg and…

Post Operative Pain, Acute

Estimated

~$10 – $8,750

AFT Pharmaceuticals, Ltd.NCT07225140

The CryoICE™ Cryoanalgesia Registry for Pain Management in Post-cardiothoracic Surgery Via Cryoablation of the Intercostal Nerves

This is a retrospective and prospective, multicenter, observational patient registry to record outcomes from patients undergoing cryoablation of the intercosta…

Post Operative Pain

Estimated

~$10 – $1,050

AtriCure, Inc.NCT05110989

Observational

EnCompass Clamp and the AtriClip in Box Lesion and Left Atrial Appendage EXclusion Procedure for the Prevention of New Onset of Atrial Fibrillation

Post Operative Atrial Fibrillation (POAF) is the most common complication of cardiac surgery. POAF incidence can exceed 50% depending on the patient baseline c…

Post Operative Atrial FibrillationAtrial Fibrillation, Postoperative

Estimated

~$10 – $8,750

AtriCure, Inc.NCT06989775

Phase 4

Adjunctive Colchicine's Effect on Inflammatory Markers and Corresponding New-Onset Atrial Fibrillation Rates Post Coronary Artery Bypass Graft Procedure: A Pilot Study

This study wants to see if the medicine colchicine can help lower inflammation and reduce the chance of developing an irregular heartbeat (atrial fibrillation)…

ColchicineInflammation in Cardiac SurgeryPost Operative Atrial Fibrillation+2 more

Estimated

~$10 – $7,500

Ayesha AtherNCT07287345

Phase 2

Temporo-masseteric Nerve Block in Post-wisdom Tooth Extraction Pain- a Randomized Study

The proposed design is a triple-blind, placebo-controlled randomized prospective phase II trial to assess the feasibility of employing the Temporo-masseteric N…

Post Operative PainImpacted Third Molar ToothMuscle Pain

Estimated

~$10 – $6,250

Rutgers, The State University of New JerseyNCT07094542

Impact of Patient Phenotypic Features on the Experience and Effectiveness of Regional Anesthesia and Postoperative Pain

The goal of this observational study is to learn about how regional anesthesia (numbing medication) affects pain in patients with different psychosocial phenot…

Acute PainChronic Post Operative PainOpioid Use

Estimated

~$10 – $750

Brigham and Women's HospitalNCT06466941

Observational

Effects of Transcutaneous Vagal Nerve Stimulation on Post-Surgical Return to Consciousness, Delirium, and Depression

This study will examine whether noninvasive, transcutaneous vagal nerve stimulation (tcVNS) can help restore consciousness in patients in the operating room an…

Post Operative DeliriumCognitive ImpairmentVagus Nerve Stimulation+1 more

Estimated

~$10 – $6,250

Northwestern UniversityNCT07610655