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Phase 2
Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial Comparing Ketamine, Stellate Ganglion Blocks and Combination Treatment to Sham Therapies for Traumatic Brain Injury-Associated Headaches and Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder (PTSD) and traumatic brain injury (TBI) with associated headache are amongst the most common injuries sustained by our deployed …
Posttraumatic HeadachePosttraumatic Stress Disorder
Northwestern UniversityNCT06608277
Observational
Project MARCH: Multisite Advancement of Research on Chronic Posttraumatic Headache
Posttraumatic headache (PTH) is a common and highly disabling consequence of traumatic brain injury (TBI) in U.S. military service members and veterans. Cognit…
Posttraumatic Headache
The University of Texas Health Science Center at San AntonioNCT05620719
Phase 2
Treatment of Acute Post-Traumatic Headache With Erenumab 140 mg, Military Service Members and Civilians With Mild TBI: A Randomized, Double Blind, Placebo Controlled, Multicenter 12-week Duration Study Followed by a 4-week Open-Label Safety Extension
This study aims to assess the effect and safety of erenumab compared to placebo for the treatment of acute posttraumatic headache (PTH) in military service mem…
Posttraumatic HeadacheMild Traumatic Brain Injury
Henry M. Jackson Foundation for the Advancement of Military MedicineNCT05049057