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Evidence-based Intervention Enhancements to Reduce Language Delays and Disorders Among Children of Parents With Substance Use Disorders
The goal of this clinical trial is to test ways to improve early language development among young children of parents with substance use disorder (SUD). Childr…
Collaborative Hub to Reduce the Burden of Suicide Among Urban American Indian and Alaska Native Young Adults
This study compares the effectiveness of a program to detect and manage suicide risk among American-Indian and Alaska Native (AI/AN) youth. Half of the partici…
Improving Colorectal Cancer Screening Decisions Through Consideration of Life Expectancy
The purpose of this study is to improve life-expectancy concordant colorectal cancer screening for adults over 75 years through design and testing of a life ex…
Leveraging Video Logs as a Bridge to Pre-exposure Prophylaxis (PrEP) With Tailored Messaging to Black Women and Their Healthcare Providers in Texas.
The primary objective of this R34 proposal is to increase willingness for PrEP initiation and PrEP initiation among Black Women (BW) and increase willingness t…
Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP
In this study, 50 pediatricians will participate in academic detailing, an evidence-based, 1-on-1 outreach education technique intended to promote clinician be…
California Hub for HIV/STI/SUD Prevention Research With Reentry Populations
The California Hub for HIV/SUD Prevention Research with Reentry Populations addresses the question: "Can the evidence-based MEPS intervention be adapted and im…
Project Safe Guard-Trauma (PSG-T): A Randomized Controlled Trial of Counseling to Promote a Secure Home Environment
The goal of this randomized controlled trial is to determine if a counseling intervention, Project Safe Guard-Trauma (PSG-T), increases secure firearm storage …
Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
This research study is an open-label Phase 1 Exploratory/Pilot clinical trial to measure the effects of the incretin mimetic, tirzepatide, on tissue, urine, bl…
Targeting Negative Affect Through Mindfulness Training in Youth at Risk for Internalizing Problems (R33)
The goal of this randomized clinical trial is to compare the effects of an online mindfulness program to an active supportive comparison condition and a no-int…
Trauma-Informed HIV Prevention for Black Women in Baltimore
U.S. epidemiological data indicates that Black women are a high-risk HIV disparity group, yet initiation of novel prevention strategies like pre-exposure proph…
Suicide Prevention In Department of Veterans Affairs Community Care Network Mental Health Settings
The study is of high importance to Veterans' health because it will study a suicide prevention intervention in a Veteran population that is at high risk of sui…
WePrEP: A Bilingual Shared Decision-making Tool to Facilitate Conversations Between Transgender Women and Their Providers as They Select an Ideal PrEP Method
HIV prevalence among transgender women (TW) in the United States is high (\~14%). The best way to reduce HIV incidence in this population is to link TW to HIV …